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Real-time transcription provides deaf and hard of hearing people visual access to spoken content, such as classroom instruction, and other live events. Currently, the only reliable source of real-time transcriptions are expensive, highly-trained experts who are able to keep up with speaking rates....
Multiple sequence alignment (MSA) is an important step in comparative sequence analyses. Parallelization is a key technique for reducing the time required for large-scale sequence analyses. The three calculation stages, all-to-all comparison, progressive alignment and iterative refinement, of the MAFFT...
Sequence alignment is the basic and most widely used method of comparing two or more biological sequences. It can be used as the first step of various sequence analysis tasks to quantify the similarities between the sequences. The goal of sequence alignment is to transform one sequence to anoth...
However, many researchers are unclear about how these methods work, how they compare to alignment-based methods, and what their potential is for use for their research. We address these questions and provide a guide to the currently available alignment-free sequence analysis tools. The online ...
The program to calculate the power of D2, D2* and D2S can be downloaded from http://meta.cmb.usc.edu/d2. Supplementary Material is available at www.liebertonline.com/cmb. 展开 关键词: alignment-free, hidden Markov model, motifs, normal approximation, power, sequence alignment, word count...
Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. The strength of these m
MAFFT online service: Multiple sequence alignment, interactive sequence choice and visualization. Brief. Bioinform. 2019, 20, 1160–1166. [Google Scholar] [CrossRef] [PubMed] [Green Version] Stamatakis, A. RAxML version 8: A tool for phylogenetic analysis and post-analysis of large phylogenies....
DNA sequence assembly, sequence alignment, contig editing, and mutation detection software for Windows and Mac OS X. View & edit sequence assemblies.
for example multiple sequence alignment or structure relaxation. Neural network models have also shown very high performance in other sequence-based tasks [33,34,35] and variant effect prediction [12,14], but there has not previously been a fully end-to-end neural network specialised VEP that ...