Cardiovascular Involvement in General Medical Conditions Sepsis and the Heart MW Merx,C Weber 被引量: 1发表: 2014年 Nitric Oxide, Sepsis and the Heart L Alarcon,T Billiar,R Simmons 被引量: 0发表: 2020年 [Sepsis and heart]. In patients suffering from severe sepsis an impairment of cardiac ...
Sepsis and the heart[J]. Circulation,2007,116 (7) :793 - 802.Merx MW, Weber C. Sepsis and the heart. Circulation 2007;116(7):793-802Merx MW, Weber C. Sepsis and the heart. Circulation 2007; 116: 793-802.Merx MW, Weber C. Sepsis and the heart. Circulation 116: 793-802, 2007...
The meaning of SEPSIS is a potentially life-threatening, systemic response of the immune system that results from the spread of pathogenic agents (such as bacteria or viruses) and their toxins to the bloodstream from a localized infection (as of the lung
The common non-specific symptoms of sepsis include increased heart rate, fever, confusion, and increased respiratory rate. More severe symptoms include hypo-perfusion that will lead to eventual multiple organ dysfunction. Mortality has decreased in the last decade with the improvement in critical care...
10 In effect, the definitions of sepsis, septic shock, and organ dysfunction have remained largely unchanged for more than 2 decades.Box 1. SIRS (Systemic Inflammatory Response Syndrome) Two or more of: Temperature >38°C or <36°C Heart rate >90/min...
and injury. Depletion of innate and adaptive immune cells through apoptosis can lead to immunosuppression. Multiple factors influence the immune response in sepsis, including co-morbidities (e.g., malignancy, diabetes, heart disease), the microbial inoculum quantity, and the pathogen’s virulence. ...
To date, the prevention of trauma-related infection/sepsis has mainly included infection prevention (e.g., surgical management, prophylactic antibiotics, tetanus vaccination, immunomodulatory interventions) and organ dysfunction prevention (e.g., pharmaceuticals, temporary intravascular shunts, lung-protective...
6 and 7 show heatmaps of the top 15 variables contributing to the increase in risk score up to 12 h prior to onset of sepsis. It was observed that clinical variables related to sepsis (e.g., temperature, white blood count, heart rate) were identified as the top contributing factors....
Severe sepsis represents 2.26 cases per 100 hospital discharges in the United States (1). With an estimate of 751,000 cases a year in the United States and a 28.6% mortality, severe sepsis is responsible for 9.3% of the deaths in this country (i.e., as m
Earlier recognition and treatment of sepsis has led to improved short-term survival; however, survivors of sepsis face complicated clinical trajectories, including an increased risk of cognitive impairment [1,2,3,4,5,6]. Sex is a major factor contributing to variability in the response to sepsis...