Sensory-related neural activity regulates the structure of vascular networks in the cerebral cortex. Neuron 83, 1117-1130. http://dx.doi.org/10.1016/j.neuron.2014. 07.034.Lacoste, B. et al. Sensory-related neural activity regulates the structure of vascular networks in the cerebral cortex. ...
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Mechanistically, olfaction excites mitral and tufted (M/T) cells, which receive sensory information from ORNs and release insulin-like growth factor 1 (IGF1) in an activity-dependent manner. Specific knockout of Igf1 in M/T cells suppresses gliomagenesis. In addition, knocking out the IGF1 ...
[27,28] It remains uncertain whether SOR is merely an associated feature arising from neural substrates shared across these disorders or whether SOR plays a causal role in the emergence and/or trajectory of the disorders' core phenotypes. While still preliminary, mounting evidence implicates the ...
These results confirm that the ahr-1 mutant cAVM neuron regulates specific behavior and thus retains the capacity to signal other neurons in the motor circuit. These results also suggest that cAVM has adopted PVD-like morphology and sensory modalities but not the synaptic output of PVD, which ...
Related to this Question Describe how the nervous system responds to stimuli. Explain the functions of sensory receptors. Explain one example of how the arrangement of neurons in a sensory system increases our ability to localize stimuli (either on our body or in the environment). ...
The sigma-1 receptor (σ1R), an endoplasmic reticulum chaperone protein, is widely distributed and regulates numerous intracellular processes in neurons. Nerve injury alters the structure and function of axotomized dorsal root ganglion (DRG) neurons, contributing to the development of pain. The σ1...
Motor function improvement is achieved through task-oriented repetitive training during functionally related dynamic movements and the provision of artificial feedback [125, 126]. Upper extremity rehabilitation is often performed via vibrotactile feedback applied to the arm or hand to guide limb movements...
The neuronal activity-driven transcriptome. Mol. Neurobiol. 51, 1071–1088 (2015). Article CAS PubMed Google Scholar Yap, E. L. & Greenberg, M. E. Activity-Regulated Transcription: Bridging the Gap between Neural Activity and Behavior. Neuron 100, 330–348 (2018). Article CAS PubMed Pub...
Following the observation that optogenetic gamma stimulation can attenuate amyloid burden5, we found that sensory gamma stimulation promotes 40 Hz neural activity in multiple brain regions including the prefrontal cortex6,7,16. Sensory gamma stimulation also attenuates Alzheimer’s disease-related patholo...