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Results were consistent in both species and demonstrated that nickel targeted and impaired microvillous OSN function, while copper targeted and impaired ciliated OSN function. This result suggests that contaminant-specific effects observed in model laboratory species extrapolate to wild fish populations. ...
We focused on the role of the ETS homolog, Pnt, because of its unique mutant phenotype, which reveals a role in limiting, rather than determining, Or67d neuron specification. With our at1 lineage marker, protein expression and gain- and loss-of-function analyses, we provide evidence that ...
The function generates text whose relative size linearly corresponds to the range of input values (i.e., synaptic weights). To identify descending neuron targets of TLHONs, we first made a ranked list of common TLHON outputs (defined as any postsynaptic partners that received ≥ 10 synapses ...
primarysensory neuronhas its cell body in a spinal ganglion or cranial nerve ganglion, the secondary sensory neuron has its cell body in the gray matter of the spinal cord or in thehindbrain, and the tertiary sensory neuron has its cell body in the thalamus. These pathways cross the midline...
(AO), dorsal neuron (dn) and neurites extending to the ventral part of the larvae. Inserts:a1Two paired 5-HT-lir cells (asterisks) lie between two FMRFamide-lir cells (asterisk) of the apical organ (AO) near the apical tuft of cilia (at). In the central part of the AO, neurites...
The discovery, found in the Feb. 2010 issue of the journalNeuron,goes against a long-held assumption that the signaling of a sound’s appearance and its subsequent disappearance are both handled by the same pathway. The new finding, which supports an emerging theory that a separate set of sy...
RNA-seq data from whole ganglia likely mainly represent the transcriptome of non-neuronal DRG cells, and at the very least under-represents neurons. Hence, to gain better insight into transcriptomic sex differences at the sensory neuron level, we purified DRG and TG sensory neuronal enriched fracti...