Senescence-associated (beta)-galactosidase is widely used as a biomarker of replicative senescence. However, it remains unknown whether this is a distinct enzyme active at pH 6, and differentially expressed in senescence, or a manifestation of an increase in the classic acid lysosomal (beta)-galact...
1. The cytochemical staining of senescence associated β-galactosidase(SA-β-GAL)was applied to cultured neurons for 6、12 and 20 days. 方法:利用SD新生鼠进行海马神经元原代培养,分别取培养6、12和20d的神经元进行衰老相关β半乳糖苷酶(SA-β-GAL)的细胞化学染色。
英文名称:senescence-associatedβ-galactosidase 英文同义词:senescence-associatedβ-galactosidase CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览senescence-associatedβ-galactosidase国外供应商中国供应商 senescence-associatedβ-galactosidase推荐供应商 ...
Although the phenomenon of cellular senescence in human cells was first described several decades ago, major progress in understanding the mechanism and the role of cellular senescence started in the late 1990s, greatly facilitated by the discovery of the Senescence-Associated Beta-Galactosidase (SABG)...
Calmodulin-like skin protein suppresses hydrogen peroxide- or ultraviolet-induced increase in senescence associated beta-galactosidase in keratinocytesCalmodulin-like skin protein (CLSP) is a secreted peptide that is restrictedly produced in skin... Y Takahara,N Miyachi,M Nawa,... - 《Proceedings for...
A high percentage of replicative senescent cells were positive for senescence-associated 尾-galactosidase activity, and displayed elevated levels of p21 and ... Kook-Hee,Kim,and,... - 《Biochemical & Biophysical Research Communications》 被引量: 160发表: 2004年 Hematide is immunologically distinct ...
Elevated levels of senescence-associated 尾-galactosidase ... K Qu,T Lin,J Wei,... - 《Nan Fang Yi Ke Da Xue Xue Bao》 被引量: 27发表: 0年 Involvement of mitogen-activated protein kinases and p21Waf1 in hydroxyurea-induced G1 arrest and senescence of McA-RH7777 rat hepatoma cell ...
Senescence-Tracker™衰老细胞近红外荧光探针能够被衰老细胞特异性表达的β-半乳糖苷酶(β-galactosidase, β-gal)特异识别并快速酶解,产生强烈的近红外荧光信号。 本探针中国授权专利号为ZL202211569064.4,相关研究成果发表在国际衰老研究领域著名期刊Aging Cell (2023. 22(8):e13896)。 绝大多数正常细胞被认为仅...
Our results show, for the first time, that PGG-induced senescence-like S-phase arrest in HepG2, Huh-7 human hepatoma cells, and SKBr3 human breast cancer cells at sublethal doses, judged by cellular morphological changes, increased senescence-associated β-galactosidase (SA-β-gal) activity,...
Expression of senescence associated-β-galactosidase and P16 in the spleen of aged rats; 衰老相关-β-半乳糖苷酶和P16在老年大鼠脾内的表达及意义3) senescence associated β-galactosidase 衰老相关β半乳糖苷酶 1. The cytochemical staining of senescence associated β-galactosidase(SA-β-GAL)was applie...