Negative symptoms in schizophrenia may be classified as primary or secondary. Primary negative symptoms are thought to be intrinsic to schizophrenia, while secondary negative symptoms are caused by positive symptoms, depression, medication side-effects, social deprivation or substance abuse. Most of the ...
Schizophrenia is phenomenologically heterogenous and includes multiple psychological domains e.g., "negative" (or "deficit") symptoms. The importance of the negative symptom complex includes long-term outcome. Carpenter et al highlighted the inherent difficulties in distinguishing between primary negative (...
negative drugs for a given ADR (Fig. 3a). Across 719 tested associations, 240 (33%) were significant and a further 20 (3%) were marginal. The proportion varies significantly across targets (Fig. 3b). A large percentage of associations were confirmed for adrenergic receptors (e.g., ADRA1A...
We found a relatively stable pattern of lower negative symptoms over two years among patients with LSI and LSA. No significant difference in serum BDNF concentrations was detected. The translational viability of using neuropsychological profiles as a possible avenue for the identification of p...
B.I. Turetsky, in The Neurobiology of Schizophrenia, 2016 Neurobiology of MMN Converging evidence from magnetoencephalography, ERP source modeling, fMRI, and PET imaging suggests that MMN is generated bilaterally in the primary and secondary auditory cortices, with perhaps a later contribution from ...
MHSE mediated the effects of the intervention on anxiety and stress symptoms. Furthermore, people with low pre-treatment MHSE reported the greatest post-intervention gains in depression, anxiety and overall distress. No effects were found for MHSE on work and social functioning. Conclusion Mental ...
Moreover, we expected to find positive associations with higher cognitive-behavioral skills and adaptive emotion regulation, and negative associations with mental health symptoms and maladaptive emotion regulation. Last, we tested for psychometric equivalence of the psychosocial functioning construct across ...
Kirkbride JB, Fearon P, Morgan C, Dazzan P, Morgan K, Tarrant J, Lloyd T, Holloway J, Hutchinson G, Leff JP, Mallett RM, Harrison GL, Murray RM, Jones PB: Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-centre AeSOP study. Arch Gen...
Associations between duration of untreated psychosis and domains of positive and negative symptoms persist after 10 years of follow-up: A secondary analysis ... LSA Jabar,HJ Srensen,M Nordentoft,... - 《Schizophrenia Research》 被引量: 0发表: 2020年 Relationship between duration of untreated ps...
29. (New) A replication-defective recombinant adenovirus virus comprising an ORF selected from the group consisting of: a) a non-phosphorylatable retinoblastoma ORF; b) a dominant negative mutant of a RAS ORF; or c) a thymidine kinase ORF of a Herpes virus; wherein i) said ORF is under...