lymphocytes,whichprovidesthefoundationforclinicaltumorimmunotherapy. 【Keywords】 StaphylococcusaureusEnterotoxins CD69 T-Lymphocytes 超抗原(superantigen,SAg)是一组细菌或病毒编 码的蛋白质分子,因其在极低浓度(1～10ng/mL)下 就可激活2%～20%的T细胞,产生极强的免疫反应 而得名[1]。T细胞对SAg的识别仅涉及特...
Cancer/testis antigens (CTAs) have been regarded as promising targets for cancer immunotherapy because of their restricted expression in adult somatic tissues, high immunogenicity and re-expression in many cancers7, 8, 9. NY-ESO-1, also known as cancer/testis antigen 1, is a protein with 18...
is hyperglycosylated in carcinoma tissue and the oncogenic function of EpCAM primarily depends on the degree of glycosylation. Inhibiting EpCAM glycosylation is expected to have an inhibitory effect on cancer. We analyzed the relationship of BAP31 with 84 kinds of tumor-associated antigens and found...
Our results suggest that fibroblasts can be genetically modified into efficient antigen-presenting cells for the induction of antigen-specific CTL response in cancer immunotherapy. Int. J. Cancer 87:427–433, 2000. © 2000 Wiley-Liss, Inc.Tae S. Kim...
immunotherapymicrobiologyinterestThe topic of immunity to fungal infections is of interest to a wide range of disciplines, from microbiology to immunology. It is of particular interest in terms of therapy of HIV-infected individuals, and patients with cancer or individuals who have received transplants...
While other methods of immunotherapy exist, immune checkpoint inhibitors, tumor infiltrating lymphocytes, tumor vaccines, and cytokine therapy are commonly used to treat melanoma. Like many other cancer treatments, immunotherapy is not without adverse effects, as toxicities represent a major obstacle. ...
While other methods of immunotherapy exist, immune checkpoint inhibitors, tumor infiltrating lymphocytes, tumor vaccines, and cytokine therapy are commonly used to treat melanoma. Like many other cancer treatments, immunotherapy is not without adverse effects, as toxicities represent a major obstacle. ...
IMMUNOTHERAPYANTINEOPLASTIC agentsINFECTIONANTIGEN presenting cellsTUMORSCYTOKINESINFLAMMATIONDENDRITIC cellsSimple Summary: Cancer stands as the second leading cause of death globally. Over the years, concerted efforts have been devoted to developing innovative and effective therapies for tumor eradication and to...