Cancer patients have a higher risk of cardiovascular disease (CVD) mortality than the general population. Low dose computed tomography (LDCT) for lung cancer screening offers an opportunity for simultaneous CVD risk estimation in at-risk patients. Our deep learning CVD risk prediction model, trained...
Advanced technologies of high-throughput genetic screening.ALibraries of siRNA, shRNA, and sgRNA were designed and constructed for delivery into tumor cells or T cells using viral vectors. The screening was categorized into LOF and GOF approaches, utilizing siRNA, shRNA, CRISPR KO, base editing, ...
Ivanovs, R.; Kivite-Urtane, A.; Ziedonis, D.; Mintale, I.; Vrublevska, J.; Rancāns, E. Association of depression and anxiety with the 10-year risk of cardiovascular mortality in a primary care population of Latvia using the SCORE system.Front. Psychiatry2018,9, 276. [Google Schol...
To explore a method for screening and diagnosing neonatal congenital heart disease (CHD) applicable to grassroots level, evaluate the prevalence of CHD, and establish a hierarchical management system for CHD screening and treatment at the grassroots level. Methods A total of 24,253 newborns born in...
Those population-level differences in blood pressure have a substantial impact on clinical outcomes for cardiovascular disease, cerebrovascular disease, and kidney disease [2, 22]. Medical treatment after screenings, such as drug administration and lifestyle improvement, may be effective, and a ...
Gradient boosting is considered one of the strongest algorithms for building predictive models and has successfully been used in various predictive models in medical research, e. g. in the development of a sepsis screening tool or in identifying cardiovascular disease [1,40,43,44]. The idea ...
Inflammatory bowel disease, screening for dysplasia - targeted biopsies, plus: Pancolitis - biopsies from the 4 quadrants each 10 cm; Segmental colitis - biopsies from the 4 quadrants each 10 cm limited to involved areas in previous examinations; Pouchitis - multiple biopsies from the pouch and ...
Nutrition and cardiovascular disease: finding the perfect recipe for cardiovascular health. Nutrients. 2016;8:363. Article Google Scholar Sieber CC. Malnutrition and sarcopenia. Aging Clin Exp Res. 2019;31:793–8. Article Google Scholar Baek M, Heo Y. Evaluation of the efficacy of nutritional...
Familial Hypercholesterolaemia is a significant risk factor for cardiovascular disease, the leading cause of death globally. Familial Hypercholesterolaemia is an autosomal, dominant genetic disorder predominantly associated with pathogenic variants in the genes LDLR, ApoB, LDLRAP1 and gain of function va...
Centers for Disease Control and Prevention. Accessed March 1, 2024. https://www.cdc.gov/cancer/dcpc/prevention/other.htm 32. Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College...