Advanced technologies of high-throughput genetic screening.ALibraries of siRNA, shRNA, and sgRNA were designed and constructed for delivery into tumor cells or T cells using viral vectors. The screening was categorized into LOF and GOF approaches, utilizing siRNA, shRNA, CRISPR KO, base editing, ...
Accordingly, systematic screening of athletes for preventing SCD would be justified if: (1) cardiovascular diseases at risk are sufficiently common to warrant the screening efforts; (2) tests to distinguish athletes … 展开 关键词: MYOCARDIAL DISEASE ...
DSPN has been defined as a symmetrical, length-dependent sensorimotor polyneuropathy attributable to metabolic and microvessel alterations as a result of chronic hyperglycemia exposure (diabetes) and cardiovascular risk covariates [5]. A simpler DSPN definition for clinical practice is the presence of ...
ICD-10-MC) [1]. Maintenance hemodialysis (MHD) is one of the main renal replacement therapies for patients with end-stage renal disease. The loss of amino acids during dialysis, the increase
Nutrition and cardiovascular disease: finding the perfect recipe for cardiovascular health. Nutrients. 2016;8:363. Article Google Scholar Sieber CC. Malnutrition and sarcopenia. Aging Clin Exp Res. 2019;31:793–8. Article Google Scholar Baek M, Heo Y. Evaluation of the efficacy of nutritional...
Predictive genetic testing for cardiovascular diseases: impact on carrier children. Am J Med Genet A. 2008;146(24):3136–46. Article Google Scholar Davidson MH. Dyslipidaemia: PCSK9 antibodies: a dividend of the genomics revolution. Nat Rev Cardiol. 2013;10(11):618–9. Article CAS PubMed ...
Screening of depression is also recommended for cardiovascular risk stratification in women (59) and in young patients (60), as well as to identify modifiable risk factors for patients in clinical practice who are at high risk of developing CVD (61) (Table 1). Table 1. Select Recommendations...
A plethora of classification models for the detection of glaucoma from fundus images have been proposed in recent years. Often trained with data from a single glaucoma clinic, they report impressive performance on internal test sets, but tend to struggle
Depression is a leading cause of disability worldwide. African American adults, compared to White adults, are half as likely to be screened for depression in primary care settings. Disparities in depression screening contribute to poor clinical outcomes,
To map ICD to phecodes, ICD-9 (Phecode Map 1.2, used for both cohorts), ICD-10 (Phecode Map 1.2b to ICD-10 beta, used for UKB), and ICD-10-CM (Phecode Map 1.2b to ICD-10-CM beta, used for HNP) to phecode maps from the Phewas catalog were used to code individuals as a...