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[8] Jazz Pharmaceuticals Announces Statistically Significant Overall Survival and Progression-Free Survival Results for Zepzelca® (lurbinectedin) and Atezolizumab Combination in First-Line Maintenance Therapy for Extensive-St...
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Limited-stage small-cell lung cancer: the current status of combined-modality therapy. Limited-stage (LS) small-cell lung cancer (SCLC) remains a therapeutic challenge to medical and radiation oncologists. The treatment of LS-SCLC has evolved... MA Socinski,JA Bogart - 《Journal of Clinical...
(see Principles of Chemotherapy in the NCCN Guidelines for Small Cell Lung Cancer). This combination replaced alkylator/anthracycline-based regimens based on its superiority in both efficacy and toxicity in the limited-stage setting. EP plus concurrent thoracic radiotherapy is the recommended therapy ...
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In the clinical practice, the first-line therapy for SCLC has been unchanged for decades, mainly the usage of chemoradiotherapy for SCLC. Although SCLC patients are sensitive to chemotherapy, recurrence arises rapidly in 80% of limited-stage SCLC and nearly all the extensive-stage SCLC cases. ...