2024年9月27日,中山大学肿瘤防治中心内科张力教授、方文峰教授团队开展的“索凡替尼+特瑞普利单抗+依托泊苷+顺铂一线治疗晚期小细胞肺癌(SCLC)患者的前瞻性临床研究”在国际期刊《信号转导与靶向治疗》(Signal Transduction and Targeted Th...
近日,中国生物制药1类新药安罗替尼联合信迪利单抗和白蛋白结合型紫杉醇二线及以上治疗广泛期小细胞肺癌(ES-SCLC)研究,在国际权威期刊《Signal Transduction and Targeted Therapy》(STTT,IF:40.8)发表。该研究揭示了这一联合方案在ES-SCLC...
小细胞肺癌(SCLC)是一种侵袭性强且进展迅速的肺癌亚型,约占所有肺癌诊断的15%。SCLC的预后极差,中位总生存期(OS)仅为7个月,约70%的患者在诊断时已处于广泛期。 2025年2月18日,国家呼吸疾病重点实验室、广州医科大学钟南山院士等人在"Signal Transduction and Targeted Therapy"期刊上发表了一篇题为"Induction che...
Emavusertib Holds Potential for Combination Therapies in AML/MDS Secondary Primary Cancer Prevention Strategies Following CAR T-Cell Therapy Are Underway Targeted Therapies for NSCLC With Nonclassical EGFR Mutations Grow Increasingly Personalized View More Recent ContentAdvertise...
近日,中国生物制药1类新药安罗替尼联合信迪利单抗和白蛋白结合型紫杉醇二线及以上治疗广泛期小细胞肺癌(ES-SCLC)研究,在国际权威期刊《Signal Transduction and Targeted Therapy》(STTT,IF:40.8)发表。该研究揭示了这一联合方案在ES-SCLC二线及以上治疗中展现出的治疗潜力,并发现了可能预测疗效的生物标志物,为提前识别...
Pharmacy Times: What are some innovative research directions or novel approaches to targeted therapy in SCLC and how might these research findings influence future treatment protocols? Higgins: I think something that we're seeing across multiple oncology disease states, but also very specifically in [...
Yazaki T, Kimoto M, Minagawa A, Maruno T, Yamanaka M, Sonehara K, Hama M, Nakamura T, Kanda S, Hanaoka M, Hachiya T. Simultaneous Acquisition of T790M Mutation and SCLC Transformation during Targeted Therapy in EGFR-Mutated Lung Adenocarcinoma: A Rare Case Report. Am J Case Rep. 2024 ...
Molecular-targeted therapyRadiotherapyMultimodalityBackground: The aim of this study is to evaluate the rate of long-term survival of more than 5 years in advanced non-small cell lung cancer (NSCLC). Methods: one-hundred and twenty-four patients with advanced NSCLC treated with chemotherapy from ...
[1]Jing Y, et al. Case report: Acute pancreatitis in lung adenocarcinoma with small cell transformation after multiple line targeted therapy. Front Oncol. 2024:14:1274034. [2] Okauchi S, et al. Distant organ metastasis patterns in lung cancer patients with pancreatic metastasis - a cluster an...
“topotecan”; targeted therapy: “cyclin-dependent kinase 4/6 (CDK 4/6),”“delta-like ligand 3 (DLL-3),”“PARP,”“trilaciclib”; biomarkers: “biomarkers,”“Schlafen 11 (SLEN11)”; other: “current,”“epidemiology,”“guidelines,”“real-world,”“second-line treatment,”“...