摘要:Many patients with schizophrenia have pronounced deficits in the use of negative feedback to guide problem solving and learning, as seen on tasks like the Wisconsin Card Sorting Test. There is now a compelling body of evidence from nonhuman primates that suggests transient decreases in dopami...
The logical progression from this exploratory qualitative study would be to generate a questionnaire to further test the veracity of this outcome. An advantage of the present methodology relates to the potential use of participants own language in the development of the item wording for a new ...
In this exploratory cross-sectional study, involving 42 patients with a diagnosis of acute paranoid schizophrenia (DSM-IV), we assessed religiosity (Religious Orientation Test) spirituality (Spiritual Transcendence Scale) and ego-pathology (Ego Pathology Inventory) and analysed any relationship with these...
First, to test whether FC between each striatal seed and the rest of the brain differed between individuals with treatment-resistant and non-refractory schizophrenia, independent-samples t-tests were conducted for these groups for each seed. To permit dissociation of effects relating to, and those ...
We will now need to conduct a larger randomized control trial to exclude this possibility and to test if rtfMRI-NF training can be used as a novel therapeutic intervention in people with SCZ and AVH. It does seem, however, that patients with SCZ and AVH do have the ability to regulate ...
Finally, to test whether the findings with HAL can be generalised to other antipsychotic drugs, we explored the effects of chronic OLZ administration on SV2A immunostaining intensity in the rat PFC and ACC (Supplementary Fig.5). In agreement with the results from HAL treatment, chronic administra...
Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic associatio