通过从单组学数据生成多组学数据的功能,scDesign3可以评估集成来自不匹配细胞的多模态数据的计算方法。 scDesign3的功能二:可解释性 图2 作为单细胞和空间组学数据的通用概率模型,scDesign3不仅可以用于生成合成数据,还具有广泛的应用。作者研究了scDesign3模型的三个重要应用:模型参数、模型选择和模型修改(图2a)。 ...
scDesign3的功能一:模拟 图1 作者验证了scDesign3作为一个逼真且多功能的模拟器,在如下四个示例设置中:(1)连续细胞轨迹的单细胞RNA测序(scRNA-seq),(2)空间转录组学,(3)单细胞表观基因组学和(4)单细胞多组学(图1)。作者展示了scDesign3生成的合成数据与测试数据保持一致。 在第一个设置中,scDesign3模拟...
作者使用scDesign3估计了不同基因随拟时序的变化和不同基因在二维空间内的变化,以及不同细胞类型内基因-基因相关性的模式。scDesign3提供了基于模型似然度的无监督度量,得以评估从数据中推断的细胞轨迹和数据的拟合程度。最后,scDesign3...
由于这种灵活性,scDesign2可以从泊松、 ZIP、 NB 和 ZINB 中选择一个计数分布,以适应每个基因的表达计数,并揭示该基因表达模式的生物学见解。 针对scDesign2的变异没有联结和现有的8个 scRNA-seq 模拟器生成10x Genomics法测量杯状细胞。A 基于实际数据(未用于...
Zero Energy Design (ZED) is a modern green architecture and mechanical design firm that provides green energy focused consulting and mechanical design services to professionals. ZED works with architects, builders, developers, building owners, institutions, prefab companies and others who are committed ...
We had a kitchen replaced by SC Design, based on the fact that 2 members of the family had used this company in the past few years. Their experience was great, and so was ours. Gemma helped with design ideas and colours. Scott came out to finalise the design. The fitting team worked...
We present a statistical simulator, scDesign3, to generate realistic single-cell and spatial omics data, including various cell states, experimental designs and feature modalities, by learning interpretable parameters from real data. Using a unified prob
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齿条齿轮设计Rack Pinion Design Double acting Single acting/Spring return ENISO5211 DR00015 DL00015 SC00015 SO00015 F04-11 DR00030 DL00030 SC00030 SO00030 F05-14 DR00060 DL00060 SC00060 SO00060 F05-F07-17 DR00100 DL00100 SC00100 SO00100 F05-F07-17 DR00150 DL00150 SC00150 SO00150 F07...
DJI Ronin-SC Challenge Accepted Watch Video With a lightweight design and superior stabilization, Ronin-SC is a 3-axis stabilizer for mirrorless cameras, allowing users to create professional footage with ease. Lightweight & Compact Opening possibilities for filmmakers and content creators in almost ...