golden hamsters (Mesocricetus auratus) and Chinese hamsters (Cricetulus griseus) are susceptible to SARS-CoV-2 infection, develop similar clinical symptoms to humans and immunity against reinfection, yet not shedding enough viral RNA to be a potential source of zoonotic transmission (Fig.2). [34,...
Fig. 1: Structure and redox properties of SARS-CoV-2 main protease (Mpro). aStructure of the Mprodimer (pdb code7KPH) highlighting the positions, structural properties and functions of cysteine residues. The two monomers of the functional dimer and corresponding cysteines are colored individually...
binding affinity to hACE2 and TMPRSS2, as well as SP’s transmembrane capacity, which should be taken into consideration in the following design of highly effective therapeutic antibodies. Currently, the efficacy of neutralizing antibodies against SARS-CoV-2 variant is decreasing, while the reasons...
golden hamsters (Mesocricetus auratus) and Chinese hamsters (Cricetulus griseus) are susceptible to SARS-CoV-2 infection, develop similar clinical symptoms to humans and immunity against reinfection, yet not shedding enough viral RNA to be a potential source of zoonotic transmission (Fig.2). [34,...
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REAGENT or RESOURCESOURCEIDENTIFIER Antibodies Rabbit polyclonal human MUC5B Santa Cruz RRID: AB_2282256 Mouse monoclonal human MUC5AC Invitrogen RRID: AB_10978001 Rabbit polyclonal SARS coronavirus nucleocapsid Invitrogen RRID: AB_1087200 Mouse monoclonal anti-acetylated tubulin Sigma-Aldrich RRID: AB_609...
Data and code availability All data reported in this paper will be shared by the lead contact upon request. This paper does not report the original code. Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.References...