6c). Moreover, while the nuclear localization of NLRC5 was intact with WT KPNB1 expression, a dominant-negative form of KPNB148 abolished nuclear import of NLRC5 (Fig. 6d), corroborating that NLRC5 utilizes a karyopherin complex for its nuclear import. Fig. 6: NLRC5 utilization of the ...
Type I and type III interferons - induction, signaling, evasion, and application to combat COVID-19. Cell Host Microbe 27, 870–878 (2020). Article CAS Google Scholar Min, Y. Q. et al. Immune evasion of SARS-CoV-2 from interferon antiviral system. Comput. Struct. Biotechnol. J. 19...
Respiratory system For COVID-19 cases, up to 20% will develop to a severe form, featured with the occurrence of COVID-19-associated ARDS, severe pneumonia, and pulmonary fibrosis.123Furthermore, several investigations have reported persistent lung injury even after clearance of SARS-CoV-2. A m...