纳入标准:①符合《病毒性脑炎的诊治》[6]中关于病毒性脑炎的诊断标准;②脑脊液宏基因组学第二代测序(metagenomic next-generation sequencing,mNGS)检测出SARS-CoV-2 RNA;③排除其他神经系统疾病。所有样本和医疗数据的获取遵循中国生物伦理法和《赫尔辛基...
SARS-CoV-2chronic liver diseasecirrhosisprioritizationvaccineSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus causing coronavirus disease 19 (COVID-19), with an estimated 22 million people infected worldwide so far although involving primarily the respiratory tract, has...
13 Further, the existing blood supply may be considered unsafe for medical and research use, as SARS-CoV-2 RNA has been found in the blood of symptomatic patients.7 However, as of this writing, the US Centers for Disease Control (CDC) and Food and Drug Administration (FDA) do not ...
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop a mild to moderate disease with virus replication restricted mainly to the upper airways, some progress to having a life-threatening...
SARS-CoV-2和SARS-CoV的刺突蛋白受体结合域(RBD)显示出高度的一致性[24,25],并且在SARS-CoV-2感染患者的血液样本中也能检测到病毒RNA[16]。因此,一个合理的假设是,除了由Fas/Fas-L和IFN/TRAIL介导的细胞活化和细胞死亡外,SARS-CoV-...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded positive ribonucleic acid (RNA) virus, is the causative agent, and multiple variants have emerged, ranging from alpha to omicron.3SARS-CoV-2, belonging to the Sarbecovirus subgenus of betacoronavirus, possesses a gen...
SARS-CoV-2 continues to evolve due to the inherent infidelity of RNA viruses that generate random mutations, population immunity and a high rate of daily infections. A high-quality mask (N-95 or KN95) or respirator is recommended for people with symptoms or exposed to someone with ...
It has been reported that SARS-CoV-2 can cause acute hemorrhagic colitis, thus providing evidence implicating the gastrointestinal tract in the transmission of SARS-CoV-2 infection [8]. Moreover, viral RNA has been identified in the stool samples of COVID-19 patients, and typical coronavirus ...
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the
SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated with cardiovascular complications including long-term outcomes. The presence of virus in cardiac tissue of patients with COVID-19 suggests this is a direct, rather than s