Kleymann G: Discovery, SAR and medicinal chemistry of herpesvirus helicase primase inhibitors. Curr Med Chem Anti-Infect Agents 2004;3:69- 83.Kleymann, G. 2004. Discovery, SAR and medicinal chemistry of herpesvirus helicase primase inhibitors. Curr. Med. Chem. Anti-Infect. Agents 3:69-83....
参考文献 [1]European Journal of Medicinal Chemistry, 2021, 221, 113511. 资源: 后台回复:2020,即得Top 200 SMALL Molecule Drugs by Sales in 2020高清结构pdf文件。 后台回复:200,即得Top 200 Brand Name Drugs by Retail Sales in 2019高清结构pd...
C Southan,P Varkonyi,S Muresan - 《Current Topics in Medicinal Chemistry》 被引量: 38发表: 2007年 SAR Index: Quantifying Structure-Activity Relationship The data in MCD and TGD are derived from the large-scale expert extraction of structure-activity relationships (SAR) from patents and journal...
National Institutes of Health (NIH)’s Molecular Libraries Program [7], manually extracted results pulled from tens of thousands of scientific papers published in medicinal chemistry journals by data contributors such as ChEMBL [8], and beyond. For the efficient use of this vast amount of ...
- 《Journal of Medicinal Chemistry》 被引量: 182发表: 2004年 Late Proterozoic African glacial era A series of large-scale glaciations occurring in the second half of the Late Riphean and Vendian are referred to as the African Glacial Era (Glacioera), wh... Chumakov, N M - 《Stratigraphy...
Alzheimer's Disease: Emerging Trends in Small Molecule Therapies. Alzheimer's disease (AD) is a highly complex and rapidly progressive neurodegenerative disorder characterized by the systemic collapse of cognitive functio... Mohamed,T.,Rao,... - 《Current Medicinal Chemistry》 被引量: 33发表: 2011...
Exploring activity cliffs in medicinal chemistry. J. Med. Chem. 55(7), 2932–2942 (2012). Article CAS Google Scholar Stumpfe, D. & de la Vega de León A, Dimova D, Bajorath J, ,. Advancing the activity cliff concept, part II. F1000Research 199, 1–11 (2014). Google Scholar ...
- 《Medicinal Chemistry》 被引量: 8发表: 2012年 Hymenoptera venom immunotherapy and field stings. Anaphylactic sting reactions in patients with Hymenoptera venom allergy are prevented by venom immunotherapy (VIT) in most patients. The aim of this study ... R Lang,T Hawranek - Journal of ...
Modern-day medicinal and computational chemists thrive in a data-rich environment, constantly seeking to uncover untapped… Read More Unlock the secrets of next-gen compounds Share your mission and let’s embark on a journey of discovery together ...
Zheng T, Chen B, et al.Small-molecule targeting of E3 ligase adaptor SPOP in kidney cancer[J]. Cancercell, 2016, 30(3): 474-484.[2] Dong Z, Wang Z, Guo Z Q, et al.Structure-activity Relationship of SPOP Inhibitors Against Kidney Cancer[J].Journal of Medicinal Chemistry, 2020.