More detailed descriptions on construction of these sets, including the definition of the non-inactive compounds, are given in the “Methods” section. Although any database can have unique identifiers (UIDs) to organize its records, the term “UID” is specifically reserved in the present study...
作者: H Oschkinat 摘要: SynonymsSynonymsLead discovery by NMR; NMR-screeningDefinitionDefinitionNMR can be used as a method for monitoring protein-ligand interactions, either by detecting protein signals or the signals of th DOI: 10.1007/978-3-540-38918-7_154 年份: 2008 收藏...
As a result, a growing interest in amide- and carbamate-based compounds is being observed among medicinal chemists [8,9]. Based on the cholinergic hypothesis that assumes the increase in the acetylcholine (ACh) level, carbamate-like drugs can be regarded as one of the mainstays for the ...