Analysis of these phospho-peptides identified Ser343, Ser358, Ser379, Thr484 and Ser587 as phos- phorylation sites on SIK2 (Fig. 1b). The identification of Ser342/ 343 was ambiguous from OrbiTrap data but data from the QTrap analysis showed that Ser343 was phosphorylated (Supplementary ...
Listen to the story of Sunu Verghese (widow of Taj hero Thomas Varghese) meeting Ratan Tata, Krishna Kumar & Raymond Bickson, MD of India Hotels; when she cried and told Ratan Tata, “I have lost everything and we will go home now (to Kerala).” And Ratan Tata’s response, “We ...
growing plant cells arrange their microtubules along the cell cortex2. A major function of the cortical microtubules in plant cells is to direct the synthesis of cellulose, a fundamental
As a kid, I was obsessed with the Arthurian legends, Merlin, Robin Hood, the Three Musketeers, and the Count of Monte Cristo. While it was an interest, I never got too into studying Medieval History as a specialty in college. Rather, my foci were US History and Eastern/Southwestern ...
pathway to the regulation of SIK2 Ser358 phosphorylation, immunoblot analysis was performed on lysates from primary mouse hepatocytes incubated with an Akt inhibitor (MK-2206) with or without hormones (Fig. 1e). As anticipated, MK-2206 blocked insulin-stimulated phosphorylation of Akt, but it ...