Entrez Gene ID:(Human) 6498 功能 RNA polymerase II core promoter proximal region sequence-specific DNA bindingtranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingchromatin bindingprotein bindingSMAD binding ...
For eligible patients living with hemophilia B, the goal of this gene therapy is to enable them to produce FIX themselves via this one-time treatment rather than having to receive frequent infusions of FIX, as is the current standard of care.1,2,4 It is currently approv...
On the other hand, MOSC-containing protein (or named mARC), SO, and XO are the three eukaryotic molybdeoprotein families, all of which were detected in almost all organisms that use Mo, indicating that they are all critical for maintaining the function of Mo in this kingdom. With regard ...
PI3K/Akt/mTOR pathway to improve targeted therapy in cervical cancer. Keywords: tumor budding;cervical cancer;RNA sequencing;differentially expressed genes;Gene Ontology;tumor immune microenvironment;immune profiling;immune database;PI3K/Akt signaling pathway...
Mole rats are exclusively subterranean and highly specialized rodents. Their long lifespans, remarkable anti-cancer mechanisms, and various distinctive adaptive features make them a useful research model. Moreover, opposing convergence of morphological t
Other microbial mechanisms of plant growth promotion may be triggered by different factors, including the presence of specific nutrients in the root exudates such as amino acids, sugars, organic acids, and phenolic compounds, the recognition of signal molecules between the microorganisms and plant ...
Liquid biopsies are an integral part of the diagnosis of cancer. Here, we have extended previous validation studies of a new targeted NGS panel to include the detection of copy number amplifications (CNAs), fusions, and exon skipping variants. Detection of these gene classes included specimens fr...
CPC;Apcmice have been genetically engineered to sporadically delete anAPCgene regulated by a Cre promoter (CDX2P-9.5NLS-Cre) to spontaneously form either flat or polypoid adenomas in the distal colon [36]. 2.3. NIR Peptide Specific for cMet ...