Crestor (rosuvastatin calcium) is a statin drug, that works by slowing the production ofcholesterolby the body, used to lower cholesterol and fats (triglycerides) in the blood and is used to reduce the chances of developing problems likeheart diseaseand strokes that can be caused, in part, by...
The HMG-CoA reductase inhibitor (statin) rosuvastatin (Crestor®) is widely available for use in the management of dyslipidemia, and was recently approved in the US to slow the progression of atherosclerosis as part of a strategy to lower low-density lipoprotein-cholesterol (LDL-C) and total ...
Rosuvastatin (Crestor), an HMG- CoA reductase inhibitor (statin), has a favorable pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and lack of metabolism by cytochrome P450 (CYP) 3A4 isoenzyme. This last property means that the potential for CYP3A4-...
In a clinical trial, involving 981 participants treated with rosuvastatin 40 mg (n=700) or placebo (n=281) with a mean treatment duration of 1.7 years, 5.6% of subjects treated with rosuvastatin calcium versus 2.8% of placebo-treated subjects discontinued due to adverse reactions. The most com...
Rosuvastatin (Crestor®) is an HMG-CoA reductase inhibitor (statin) that has both lipid-lowering and anti-inflammatory effects. The drug has various indications in the US, including the primary prevention of cardiovascular disease (CVD) in patients with no clinical evidence of coronary heart disea...
In a clinical trial, involving 981 participants treated with rosuvastatin 40 mg (n=700) or placebo (n=281) with a mean treatment duration of 1.7 years, 5.6% of subjects treated with rosuvastatin calcium versus 2.8% of placebo-treated subjects discontinued due to adverse reactions. The most com...
1a1b1c1dCRESTOR® (rosuvastatin) [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2024. ^Lipitor® (atorvastatin calcium) [prescribing information]. Morgantown, WV: Viatris Specialty LLC, 2024. ^Zocor® (simvastatin) [Prescribing Information]. Jersey City, NJ: Organon ...
1a1b1c1dCRESTOR® (rosuvastatin) [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2024. ^Lipitor® (atorvastatin calcium) [prescribing information]. Morgantown, WV: Viatris Specialty LLC, 2024. ^Zocor® (simvastatin) [Prescribing Information]. Jersey City, NJ: Organon ...
Crestor (rosuvastatin calcium) AstraZeneca Pharmaceuticals, Wilmington, Del (2003) 30. [prescribing information] Lipitor (atorvastatin calcium) Pfizer Ireland Pharmaceuticals, Dublin, Ireland (2004) 31. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipo...
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. Mo...