Rosuvastatin, also known as Crestor, is a statin medication used to prevent cardiovascular disease in high-risk individuals and to treat abnormal lipids. The solute carrier organic anion transporter family member 1B1 gene (SLCO1B1) encodes OATP1B1, which is found on the basolateral (sinusoidal)...
Rosuvastatin (Crestor), an HMG- CoA reductase inhibitor (statin), has a favorable pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and lack of metabolism by cytochrome P450 (CYP) 3A4 isoenzyme. This last property means that the potential for CYP3A4-...
Rosuvastatin lowers blood cholesterol levels by decreasing the amount of cholesterol made by your liver and by increasing the breakdown of bad cholesterol. How is rosuvastatin supplied (dosage forms)? Rosuvastatin is available as Crestor and generic rosuvastatin in the following dosage forms that are ...
used to lower cholesterol and fats (triglycerides) in the blood and is used to reduce the chances of developing problems likeheart diseaseand strokes that can be caused, in part, by high cholesterol levels. It is often recommended to use Crestor in conjunction with a...
Rosuvastatin, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid (Crestor), is oneof the more recently introduced statins in the United States.As with all statins, there is a concern of rhabdomyolysis andas such, the...
Rosuvastatin (Crestor®) is an HMG-CoA reductase inhibitor (statin) that has both lipid-lowering and anti-inflammatory effects. The drug has various indications in the US, including the primary prevention of cardiovascular disease (CVD) in patients with no clinical evidence of coronary heart disea...
Rosuvastatin (Crestor), an HMG- CoA reductase inhibitor (statin), has a favorable pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and lack of metabolism by cytochrome P450 (CYP) 3A4 isoenzyme. This last property means that the potential for CYP3A4-media...
Crestor, Ezallor Related treatment guides High Cholesterol Atherosclerosis High Cholesterol, Familial Heterozygous High Cholesterol, Familial HomozygousFurther information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Medical...
Prescription CRESTOR is used: to reduce the risk of major adverse cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke or the need for procedures to improve blood flow to the heart called arterial revascularization in adults who do not have known heart disea...
Administer CRESTOR at least 2 hours before aluminum and magnesium hydroxide combination antacids INDICATIONS To reduce the risk of major adverse cardiovascular (CV) events (CV death, nonfatal myocardial infarction, nonfatal stroke, or an arterial revascularization procedure) in adults without established...