Chen S, Su Y, Wang J (2013) ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differ- entiation, and maturation. Cell death & disease 4: e722.Chen S, Su Y, W
Platelet production is a result of MK apoptosis, which may be caused by elevated levels of ROS. Open Questions Which NOX isoform is responsible for the different stages of thrombocytopoiesis, including MK proliferation, differentiation, maturation, and fragmentation? Where is the boundary ...
We also confirmed that ROS-mediated miR-21-5p inhibition participated in cell apoptosis and proliferative inhibition induced by Cr(VI). Furthermore, programmed cell death protein 4 (PDCD4), the up-regulation of which was related to ROS over-production, was predicted and verified as a target ...
The clearance of ROS alleviated the inhibition of the PPAR/RXR pathway and lightened apoptosis and autophagy under acetochlor stress. Overall, these results revealed that acetochlor exposure triggered BCL2/BAX/Casp3-cascaded apoptosis and Beclin1-dependent autophagy through ROS-mediated PPAR/RXR ...
ROS-mediated NLRP3 inflammasome activation and lytic cell death in RSV-infected macrophages. Signal 1: Activation of the TLR/Myd88/NF-κB pathway promotes the expression of NLRP3,pro-IL-1β, and pro-IL-18. Signal 2: RSV-induced ROS overproduction and potassium (K+) efflux as well as mit...
related to oxidative stress, endogenous ROS have also been shown to function as signaling molecules at lower concentrations. The overall role of ROS in sensory signaling is poorly understood but the acutely sensitive response of mdIV neurons to ROS-mediated activation is consistent with a routine ...
Thus, a Zn-MOF hydrogel (Gel@ZIF-8) is prepared to regulate ROS-mediated inflammatory microenvironment. In vitro experiments show that Gel@ZIF-8 has good antibacterial effect and cell biocompatibility. In the AD-induced mouse model, Gel@ZIF-8 can significantly enhance the therapeutic effect, ...
RSL3 enhances ROS-mediated cell apoptosis of myelodysplastic syndrome cells through MYB/Bcl-2 signaling pathwayArticle Open access Published: 02 July 2024 Volume 15, article number 465, (2024) Cite this article Download PDF You have full access to this open access article ...
Erratum: ROS-mediated vascular homeostatic control of root-to-shoot soil Na delivery in Arabidopsis (EMBO Journal (2012) 31 (4359-4370) DOI: 10.1038/emboj.2012.273)We performed array comparative genome hybridization (aCGH) analyses of ... C Jiang,E Belfield,A Mithani,... 被引量: 0发表: ...
Sarkar, Alpha-Solanine induces ROS- mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway, Cell death Dis. 6 (2015), e1860.Hasanain M, Bhattacharjee A, Pandey P, Ashraf R, Singh N, Sharma S, Vishwakarma AL, Datta D, Mitra K, Sarkar...