Results Comparison oxidative stress of to Responses to cultured murine cOorxnideaalteipviethSeltiarel psrsoIgnendiutocrecdelblsy(THK2EO22).1 6 anWdecfuilrtsutraepdpmlieadtuHre2mO2u-riinndeuccoerd- neal epithelial cells (MCE), and measured the cell viability by CCK-8 assay. The cell ...
Relative fold change of mRNA level was quantified by comparison with cells transfected with scramble siRNA without stimulation (mock). (g,h) IL-6 and IL-8 cytokine production under normal and ROS-stimulated condition was quantified by MSD. (i) Relative enrichment of H3K4me1 at the promoter ...
B. Statistical comparison of flap survival areas across groups, showing that MaR1 significantly improved flap survival. C. Perfusion images of flaps from each group, with laser Doppler imaging illustrating blood flow on day 7 post-operation. D. Quantitative analysis of blood flow intensity across ...
After 24 h, the cells were treated with vehicle, C2 ceramide, or rosiglitazone and incubated for another 24 h. The luciferase-reporter assay was performed using a Dual-Luciferase Reporter Assay kit (Promega). Relative reporter activity was measured by determining the ratio of firefly to Renilla-...
AXL x RET x ROS1 x TYRO3 x Tie-2 x TrkB x VEGFR1 x VEGFR2 x VEGFR3 x c-Kit x c-Met 作用机制 AXL抑制剂(AXL受体酪氨酸激酶抑制剂)、RET抑制剂(酪氨酸蛋白激酶受体RET抑制剂)、ROS1抑制剂(原癌基因酪氨酸蛋白激酶ROS抑制剂) 治疗领域 ...
Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6) -carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free Radic Biol Med. 1999;27:146–59. Article CAS PubMed Google Scholar...
Although both lactones exhibited drug like properties, IDET was relatively effective in comparison to DET. IDET suppressed the proliferation of both invasive and non-invasive breast cancer cell lines. IDET also suppressed the colony formation and migration of breast cancer cells. The assays for ...
NAD+ratio in biological replicates. Data are pooled from three experiments forn = 6 biological replicates, with error bars representing mean ± S.D.a,d,eOne-way ANOVA was performed followed by Tukey’s multiple comparison’s test.b,cTwo-tailed student’st-test was performed.p-...
*P < 0.05, ***P < 0.001 and ****P < 0.0001, n = 6 dishes, 20 fields per dish, Welch's ANOVA followed by Dunnett's T3 multiple comparison test. D. Co-treatment with ROS scavenger glutathione inhibits the menadione-induced Parkin translocation. The percentage of PC6 cells with Parkin-...
2D). L6H9 showed a comparable anti-inflammatory effect with the positive comparison curcumin (Fig. 2A–D). Download: Download high-res image (2MB) Download: Download full-size image Fig. 2. L6H9 inhibits HG-induced inflammation and oxidative stress in H9c2 cells. (A–D) L6H9 inhibits NF...