View further author informationcmadhavareddy@gmail.com dlomada@yahoo.comDakshayani LomadaView further author informationManjula BhanooriView further author informationSriram ChittaView further author informationVajra C. ReddyView further author information...
While sharing Foxp3 expression and much of the core Treg transcriptome, unique markers and features have been ascribed to each of these populations (Table 1). After development and maturation in the thymus, Tregs migrate to non-lymphoid tissues. Skin Tregs, for example, accumulate during neonatal...
P. 2004. The thymus during HIV disease: role in pathogenesis and in immune recovery. Curr. HIV Res. 2:177.Ye P, Kirschner DE, Kourtis AP. The thymus during HIV disease: role in pathogenesis and in immune recovery. Curr HIV Res. 2004;2:177-83....
Therefore, immunomodulatory agents may hold promise for enhancing thymic recovery and immune reconstitution in INRs. Thymosin α1 (Tα1), a synthetic thymic polypeptide homologous to a natural product isolated from thymo- sin fraction 5 of calf thymuses, has emerged as a poten- tial candidate [...
In a model resembling Epstein-Barr Virus-associated lymphoproliferative disease, activation of latent membrane protein 1 in B cells resulted in lymphomas that were efficiently controlled by T cells. CD4 T cells eliminated lymphomas in vivo in a cytotoxicity-independent, IFNγ-independent and TNFα-...
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Cherwinski HM, Schumaker JH, Brown KD, Mosmann TR: Two types of mouse helper T cell clone: J Exp Med 166: 1229, 1987 PubMedCASGoogle Scholar Chused TM, McCoy KL, Lai RB, Brown EL, Bake PJ: Multigenic basis of autoimmune disease in New Zealand mice. In Concepts in Immunopathology, ...
The importance of thymus in the pathogenesis of the chronic phase of hypertension in mice following partial infarction of the kidney. Acta Pathol Microbiol Scand A 1977; 85: 539–547. CAS PubMed Google Scholar Norman Jr RA, Galloway PG, Dzielak DJ, Huang M . Mechanisms of partial renal ...
NKT cells are a unique subset of thymus-derived T cells that carry a functional antigen (Ag) receptor but also display similarities with innate immune cells through their rapid activation in response to multiple lipid Ags and/or cytokines. Despite their relative low numbers at mucosal sites, NKT...