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The complex bidirectional communication between the gut and the brain is finely orchestrated by different systems, including the endocrine, immune, autonomic, and enteric nervous systems. Moreover, increasing evidence supports the role of the microbiome and microbiota-derived molecules in regulating such ...
The authors declare no competing interests. Supplementary information Supplemental Data. About this article Cite this article Zemanová, N., Anzenbacher, P., Zapletalová, I.et al.The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice...
Research into the microbiome-the indigenous microbial communities (microbiota) and the host environment that they inhabit-has changed clinicians' ideas about microbes in human health and disease. Perhaps the most radical change is the realization that most of the microbes that inhabit our body supply...
1. The human gut microbiome interaction with the immune system in age and disease 2. The gut microbiome and age-related macular degeneration 3. The gut microbiome and retinal artery occlusion 4. The gut microbiome and central serous chorioretinopathy 5. The gut microbiome and inflammatory eye ...
The gut microbiota has important functions in metabolic processing, such as energy production, immune cell development, food digestion, and epithelial homeostasis. It has been increasingly recognized that a dysregulated gut microbiome contributes in a significant way to a variety of diseases, including ...
inflammatory astrocyte defence. The state of NK cells is modulated by systemic factors, and in particular, the production of IFN-γ depends on the gut flora. Depletion of the microbiome by treatment with antibiotics resulted in a substantial decrease of the IFN-γ producing meningeal NK cells, ...
It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while in recent years, accumulating evidence has demonstrated that the gut microbiome and its metabolites also play a crucial role in the onset and development of many metabolic diseases, including obesity...
The human GI tract is the largest immune organ in the body and plays a critical role in the immune response to pathogenic infection or commensal intrusion9. Trillions of microbes live inside the GI tract. Those microbes and their genes, collectively known as the human gut microbiome, modulate ...