microbiome/microbiotanonalcoholic fatty liver diseasenonalcoholic steatohepatitisNonalcoholic fatty liver disease (NAFLD) is the hepatic manifesta- tion of cardiometabolic syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly becoming the most prevalent liver disease worldwide...
The role of the microbiome in NAFLD and NASH. EMBO Mol. Med. 11, e9302 (2018). PubMed Central Google Scholar Boursier, J. et al. The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota. Hepatology 63,...
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34Kolodziejczyk AA, Zheng D, Shibolet O, Elinav E. The role of the microbiome in NAFLD and NASH. EMBO Mol Med 2019;11:e9302View Article 35Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. N Engl J Med 2016;375:2369-2379View Article 36Smith PM, Howitt MR...
Kolodziejczyk, A. A., Zheng, D., Shibolet, O. & Elinav, E. The role of the microbiome in NAFLD and NASH.EMBO Mol. Med.11, e9302 (2018). PubMed CentralGoogle Scholar Boursier, J. et al. The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift...
Therefore, targeting the gut microbiome and relevant metabolic pathways would be effective therapeutic treatments for many metabolic diseases in the near future. This review will summarize information about the role of the gut microbiome in organism metabolism and the relationship between gut microbiome-...
Emerging Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease: From Composition to Function The gut microbiome, a diverse microbial community in thegastrointestinal tract, plays a pivotal role in the maintenance of health. The gut microbiome metab... SR Sharpton,V Ajmera,R Loomba - 《...
providing evidence for the role of the microbiome in the metabolism of carnitine to TMA and TMAO. (Tang and Hazen2017; Yap et al.2008) Fig. 1 Pathways of trimethylamine (TMA) formation by gut microbiota and cycling of TMA to trimethylamine N-oxide (TMAO). GrdH, glycine betaine reductase....
The role of the microbiome in NAFLD and NASH. EMBO Mol. Med. 11, e9302 (2019). Sharon, G. et al. Specialized metabolites from the microbiome in health and disease. Cell Metab. 20, 719–730 (2014). Article CAS PubMed PubMed Central Google Scholar Abu-Shanab, A. & Quigley, E. ...
The role of the microbiome in NAFLD and NASH. EMBO Mol. Med. 11, e9302 (2019). Article PubMed Google Scholar Tripathi, A. et al. The gut–liver axis and the intersection with the microbiome. Nat. Rev. Gastroenterol. Hepatol. 15, 397–411 (2018). Article CAS PubMed PubMed Central...