Role for steroids in treatment of Pneumocystis carinii pneumonia in AIDS. Lancet 1987; 2: 519.Mottin D, Denis M, Dombret H, Rossert J, Mayaud Ch, Akoun G (1987) Role for steroids in treatment of pneumocystis carinii pneumonia in AIDS. Lancet II:519...
Sex steroids skew ACE2 expression in human airway: A contributing factor to sex differences in COVID-19? Am J Physiol - Lung Cell Mol Physiol, 319 (2020), pp. L843-L847, 10.1152/AJPLUNG.00391.2020 View in ScopusGoogle Scholar 10 A Salonia, M Pontillo, P Capogrosso, et al. Severely ...
Cholesterol is the end product of the sterol biosynthetic pathway in animal cells. The sterol molecule arose necessarily with the advent of an aerobic environment (Bloch, 1983), making it a relative latecomer in the evolutionary development of living cells. Perhaps, as a consequence, sterols are ...
The case for treatment in head injury is unproven. Consideration should be given to treating all those patients who develop acute respiratory distress syndrome (ARDS), although treatment should be deferred to the later (fibroproliferative) stages. The role of steroids in sepsis is complicated and,...
Infectious diseases of the lung (Table 8) Table 8 The role of leptin in infectious diseases of the lung Full size table Pneumonia Recently, several reports have identified a role for leptin in regulating immune function [24, 25] while leptin levels acutely increase during inflammation, infection...
In a retrospective study of respiratory infections conducted in January 2020 (early in the epidemic) in central Wuhan showed that among 366 children, SARS-CoV-2 was detected in only 6 (1.6%) children [24]. The Chinese novel coronavirus pneumonia emergency response epidemiology team analyzed 72,...
CONCLUSIONS: In the era of aggressive medical management for ulcerative colitis with both steroids and cyclosporine, the complications of immunosuppression may be significant, including opportunistic pneumonia. Prophylaxis againstP. carinii pneumonia with sulfa antibiotics should be considered, especially in ...
In addition, we observed increased numbers of myofibroblasts (Fig. 2) and TNF-␣ and TGF1- immunoreactive cells (Fig. 3) in all Ureaplasma-infected in- fants compared with noninfected gestational controls and infants who died with pneumonia from other causes (55,56). The increase in ...
Taking into consideration all of the above, it is evident that estrogen levels are capable of modulating lung inflammation and damage, which could potentially influence the outcome of respiratory diseases such as that of COVID-19 pneumonia caused by SARS-CoV-2. Estrogens' role has been studied ...
The currently available treatments, for example, bronchodilators and steroids, provide only symptomatic relief through bronchial smooth muscle relaxation and inhibition of inflammation. Hence, there is an unmet medical need for promising therapeutic targets with the potential to halt the progressive ...