For many years, idiopathic nephrotic syndrome has been classified based on the patient’s response to steroids: as steroid-sensitive or steroid-resistant. SRNS, most commonly focal segmental glomerulosclerosis (FSGS) in histology, has long been thought as an immune-mediated disease, either with or ...
Two patients died (one each from pneumonia and progressive disease). Conclusions This ongoing phase 1 trial is the first study reporting clinical activity of the JAK inhibitor RUX with steroids for MM. These results demonstrate that RUX with only steroids is also well tolerated and shows promising...
I am very sorry to have to say that Anne "Tree" Coley passed away of pneumonia January 6, 2014. She merely thought she had a bad case of the flu, and did not get to the hospital soon enough. Marilyn Gilligan, Nancy Filbert, and Anne "Tree" Coley ...
37 One zanamivir-resistant virus with dual hemagglutinin and neuraminidase mutations has been reported in an immunosuppressed child receiving prolonged nebulized zanamivir for treatment of influenza B pneumonia38; the specific mutations responsible for resistance in the virus isolated in our study have not...
pneumoniasevere systemic inflammationmortalitycorticosteroidssteroids.Background: This study aimed toevaluate the effectiveness and safety of intermediate to high doses of methylprednisolone in patients with COVID-19 pneumoClimente-Martí, MónicaRuiz-Millo, Oreto...
their EVs do not cause undesired immune responses due to fewer stimulatory HLA-complex molecules and surface co-stimulators.101,102In COVID-19 treatment, MSCs administration may potentially cause coagulopathy, which synergizes with COVID-19 pneumonia and deteriorates the patients’ condition. In compa...
reported that IV administration of remdesivir yielded promising results in the treatment of a patient with COVID-19 recovering from pneumonia in the USA [31]. In order to evaluate the efficacy and safety of the drug in patients with COVID-19, a randomized, placebo-controlled, double-blind, ...
Hospitals regularly change the drugs they use for conditions like flu and pneumonia as new data comes out. “What’s unusual is to change practice so quickly,” she says. “That’s just the reality of a global pandemic, with a disease we’ve never seen before.” Most of the changes in...
Primary infectious concerns are Pneumocystis jiroveci pneumonia (PCP), varicella zoster virus (VZV), and cytomegalovirus (CMV). Patients should be placed on prophylactic therapy for PCP and VZV infection/reactivation while on alemtuzumab and for several months thereafter.[51,52] Monitoring for CMV ...
"Indeed, using amoxicillin to treat chest infections in children not suspected of having pneumonia is not likely to help and could be harmful. Overuse of antibiotics, which is dominated by prescribing of antibiotics in primary care, particularly when they are ineffective, can lead to side effects...