The final phase 4 continues to the next rapid depolarization. The action potential is the result of a concerted action of inward (depolarizing) and outward (hyperpolar-izing) ionic currents. The outward component is carried by K + ions through potassium-permeable transmembrane proteins, the ...
The role of potassium in the body is to control the muscles, nervous system and kidney activity, in order to maintain normal heart beat, also need the right amount of potassium. In calcium binding, it has a lower blood pressure. 翻译结果2复制译文编辑译文朗读译文返回顶部 ...
Sugar-sweetened beverages (SSBs) are a major source of added sugars in the diet. A robust body of evidence has linked habitual intake of SSBs with weight gain and a higher risk (compared with infrequent SSB consumption) of type 2 diabetes mellitus, cardi
- 《Am J Physiol Heart Circ Physiol》 被引量: 329发表: 2000年 Mitochondrial ATP-Sensitive Potassium Channel Plays a Dominant Role in Ischemic Preconditioning of Rabbit Heart Background: The ATP-sensitive potassium (KATP) channel has been shown to be important in the ischemic preconditioning (IPC...
In isolated porcine and canine coronary artery and vein short-lasting exposure (8 min) to hypoxia (pO2 less than 20 mm Hg) evoked an increase of tone (6-34% of maximum contraction to potassium chloride). In arterial preparations of both species this response was significantly more pronounced...
Open-state substructure of inwardly rectifying potassium channels revealed by magnesium block in guinea-pig heart cells. 1. Outward single-channel currents through inwardly rectifying K+ channels of cardiac myocytes were studied in the open cell-attached configuration to clar... Matsuda,H - 《J Phys...
Mitochondrial ATP-sensitive potassium (mitoK(ATP)) channels play a key role in ischemic preconditioning of the heart. However, the mechanism of cardioprote... M,Murata,Akao,... - 《Circulation Research》 被引量: 1128发表: 2001年 Cardioprotective effects of sarcolemmal and mitochondrial K-ATP ...
Objective: Proinflammatory cytokines are known to play roles in ischemia-reperfusion injury of the heart, kidney, small bowel, skin, and liver. Little is known about their roles in ischemia-reperfusion injury of the lung. This study was undertaken to define the role of 2 proinflammatory cytokines...
Thioredoxin-interacting protein (TXNIP) is commonly considered a master regulator of cellular oxidation, regulating the expression and function of Thioredoxin (Trx). Recent work has identified that TXNIP has a far wider range of additional roles: from re
The young rat adjusts its food intake so precisely to its energy needs that its fat stores remain almost constant. Considerable variation in food intake is... GC Kennedy - 《Proc R Soc Lond B Biol Sci》 被引量: 2884发表: 1953年 Regulation of active sodium and potassium transport in the...