Structure and function of cardiac sodium and potassium channels. Am J Physiol. 1997;273(2 Pt 2):H511–25.Roden, D. M.; George, A. L., Jr. Structure and function of cardiac sodium and potassium channels. Am. J. Physiol., 1997, 273, H511- H525....
and most-functionally diverse family of ion channels encoded in the human genome and have a critical role in the restitution of cardiac action potentialsLoss-of-function mutations in the α and β subunits that conductIKs,IKr, andIK1are associated with long QT syndrome (LQTS)Genotype-specific ...
Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel The principal voltage-sensitive sodium channel from human heart has been cloned, sequenced, and functionally expressed. The cDNA, designated hH1, encodes a... ME Gellens,AL George,...
21 - Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias E Delpón,J Jalife - Elsevier Inc. 被引量: 0发表: 2022年 Neuronal KCNQ potassium channels:physislogy and role in disease family of potassium channels is exceptional: mutations in four out of...
Hyperkalemia can cause fatigue, muscle pains, irregular heartbeat, and in severe cases cardiac arrest and death. What is the range for normal potassium levels? Normal potassium levels should range between 3.7 and 5.2 mmol/L. These values can be detected via a blood test to find potassium ...
Optogenetic control of cardiac function. Science 330, 971–974 (2010). Article ADS CAS Google Scholar Chow, B. Y. et al. High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 463, 98–102 (2010). Article ADS CAS Google Scholar Ihara, K. ...
目的 探讨门冬氨酸钾镁联合胺碘酮对慢性心力衰竭并室性心律失常患者心功能的影响。方法 选择232例慢性心力衰竭并室性心律失常患者,用随机数字法分为观察组和对照组,每组116例。对照组采用胺碘酮治疗,观察组在胺碘酮基础上加用门冬氨酸钾镁。治疗前后,检测两组患者的血压、心率、P-R与Q-T间期、左室舒张末期内径(LVD...
In subject area: Agricultural and Biological Sciences The voltage-gated potassium channels carry outward potassium currents in its operating voltage range and are responsible for repolarizing a cell. From: Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle, 2018...
Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with m... BACKGROUND: Because the effects of an aldosterone receptor antagonist on transcriptional factors and mRNA expression have not been fully examined...
The transient -sensitive outward current, Ito, is one of the ionic currents involved in the repolarization of cardiac action potentials. It is present in several species (, , ) but not in ventricle. It induces both a marked lowering of the ventricular action potential plateau level and an ear...