doi:10.1007/978-1-4612-2596-6_15Fritz MarkwardtSpringer New YorkFritz Markwardt. "The Role of Potassium Ions in the Control of Heart Function: Ion Channels and Ion Pumps" 317-348.
The effect of increased potassium conductance on the genesis of R-wave amplitude increase during acute myocardial ischemia has been studied in the isolated perfused rat heart by simultaneously recording the R-wave amplitude of epicardial electrograms (VEE), heart rate (HR), coronary flow rate (CFR...
Conflicting reports regarding the role of some cytokines in inducing cardiac dysfunction in heart failure and different types of cardiomyopathies seem to be due to differences in the nature, duration, and degree of heart disease as well as the concentrations of some cytokines in the circulation. ...
Other signalling pathways may show cross-talk with this primary mechanism, but we suggest that a role for mitochondrial potassium channels is unlikely. The evidence for their activity in isolated mitochondria and cardiac myocytes is reviewed and the lack of specificity of the pharmacological agents ...
The influence of hypoxia on the activity of voltage-gated potassium channel in pulmonary artery smooth muscle cells(PASMCs) of rats and its roles in the pathogenesis of chronic pulmonary heart disease were investigated. Eighty male Sprague-Dawley rats were randomly allocated into control group(n=10...
Vascular complications in pregnancy (e.g. preeclampsia) are a major source of maternal and foetal morbidity and mortality, and may be due to excessive release of placental syncytiotrophoblast-derived extracellular vesicles (STBEVs) into the maternal circ
Inhibitors of the NLRP3 inflammasome and blockers of IL-1β and IL-18 activity have been shown to reduce injury to the myocardium and pericardium, favour resolution of the inflammation and preserve cardiac function. In this Review, we discuss the components of the NLRP3 inflammasome and how ...
Calcium/calmodulin-dependent protein kinase II and potassium channel subunit Eag similarly affect plasticity in Drosophila Proc. Natl. Acad. Sci. U. S. A., 91 (1994), pp. 10044-10048, 10.1073/pnas.91.21.10044 Google Scholar Hamdan et al., 2009 F.F. Hamdan, J. Gauthier, D. Spiegelman,...
The transmembrane organization of a potassium channel from Streptomyces lividans has been studied using site-directed spin labeling techniques and electron... E Perozo,DM Cortes,LG Cuello - 《Nature Structural Biology》 被引量: 537发表: 1998年 Mechanism of odorant adaptation in the olfactory receptor...
Magnesium is one of the ten essential metals in humans, the fourth most abundant cation, after calcium, potassium, and sodium, and the second most prevalent intracellular cation in human tissues [1]. Magnesium is a multivalent cation, pivotal for many biochemical and physiological processes, being...