Sarvetnick N,Jie HB.The role of NK cells and NK cell receptors in autoimmune disease[J].Autoimmunity,2004,37(2):147.153.Jie HB and Sarvetnick N. The role of NK cells and NK cell receptors in autoimmune disease. Autoimmunity. 2004; 37(2):147-153....
Cold target inhibition analysis and assessment of susceptibility to cytotoxic T lymphocytes (CTL) suggested that the NK resistance of ASL1 was due to the lack of expression of a relevant target structure(s) required for NK recognition. The role of NK cells in regulating the growth of the ...
Using radiation chimeras constructed in a strain of mice that is chronically depleted of Natural killer (NK) cells, but not NKT cells, we have examined the role of NK cells in the development of ANA in this context. Our results show that in the presence of intact T cell help depletion ...
85 ROLE OF NK CELLS IN REJECTION OF T-DEPLETED BM GRAFTS The role of NK and T cells for rejection of fully allogenic (BALB/c into C57B1/6J) T cell depleted BM was investigated in a murine model using congenitally... O Schofr,HJ Ünr,F Zpp,... - 《Pediatric Research》 被引量:...
The role of natural killer (NK) cells in the control of tumor metastasis, h~ Tumor Invasion and Metastasis - Hanna - 1982 () Citation Context ...nst tumors (1, 2). NK ceils, nonadherent and nonphagocytic lymphoid cells found in normal individuals, appear to be an important component ...
Tumours often take evasive action to avoid protective NK cell responses. Among the evasion mechanisms are loss of the corresponding ligands, shedding of such ligands in a manner that systemically inhibits NKG2D responses, persistent stimulation of NK cells and/or T cells in a manner that desensitize...
Genome-wide transcriptome analysis of NKG2a/c+CD8+ T cells from AGM revealed the expression of NK cell receptors, and of molecules with cytotoxic effector, gut homing, and immunoregulatory and gut barrier function, including CD73. NKG2a/c+CD8+ T cells correlated negatively with IL-23 in the...
Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA Stress-inducible MICA, a distant homolog of major histocompatibility complex (MHC) class I, functions as an antigen for γδ T cells and is frequently expr... S Bauer,V Groh,J Wu - 《Science》 被引量: ...
As CD4+ T cells from IL-10(-/-) mice will cause colitis when transferred into recombinase-activating gene (Rag)-deficient recipients, we considered the possibility that the recipients' NK cells could be an important source of IFN-gamma for the development of colitis. Therefore, the ability ...
nature publishing group REVIEW The role of IL-13 and NK T cells in experimental and human ulcerative colitis IJ Fuss1 and W Strober1 Recent studies that have evaluated the immunologic factors that mediate the development of the two forms of inflammatory bowel disease, namely Crohn's disease ...