Archives of Physiology and BiochemistryFranco R, Schoneveld OJ, Pappa A, Panayiotidis MI (2007) The central role of glutathione in the pathophysiology of human diseases. Arch Physiol Biochem 113(4–5):234–258Franco R et al (2007) The central role of glutathione in the pathophysiology of ...
Issue Journal of Cellular and Comparative Physiology Volume 9, Issue 2, pages 207–216, February 1937Additional Information How to Cite Machlis, S. and Blanchard, K. C. (1937), The role of glutathione in the metabolism of yeast. J. Cell. Comp. Physiol., 9: 207–216. doi: 10.1002/jc...
Learning about glutathione and what it does in the body has been the most important medical discovery for us, because applying this knowledge took most of the pain away, brought Ray’s condition under enough control to allow him to continue living in all meanings of this word. ...
International journal of general medicineGhezzi P. Role of glutathione in immunity and inflammation in the lung. Intern J Gen Med 2011:4:105-13.P. Ghezzi, "Role of glutathione in immunity and inflammation in the lung," International Journal of General Medicine, vol. 4, pp. 105-113,...
Concentrations of rhein and nitrofurantoin in the micromolar range induce Ca2+ release and the development of increased inner membrane permeability in liver mitochondria. Both compounds inhibit the mitochondrial glutathione reductase causing a depletion of GSH and an accumulation of GSSG in energized mitocho...
Journal of Investigative SurgeryJefferies H,Bot J,Coster J, et al.The role of glutathione in intestinal dysfunction. Journal of Investigative Surgery . 2003Jefferies H, Bot J, Coster J, Khalil A, Hall JC, McCauley RD. The role of glutathione in intestinal dysfunction. J Invest Surg. 2003;...
The function of glutathione in xenobiotic and heavy metal detoxification, plant development, and plant-pathogen interactions is also briefly discussed. Several lines of evidence indicate that glutathione and glutaredoxins (GRXs) are implicated in the response to oxidative stress through the regeneration ...
Building on this knowledge, introduction of anthocyanin-related glutathione transferases into a heterologous biosynthetic pathway in baker’s yeast results in >35-fold increased anthocyanin production. In addition to unravelling the long-elusive anthocyanin biosynthesis, our findings pave the way for the ...
Glutathione-S-transferases (GSTs) are a family of Phase II detoxification enzymes that catalyse the conjugation of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds. GSTs are divided into two distinct super-family members: the membrane-bound microsomal and cytos...
Proteins can form reversible mixed disulfides with glutathione (GSH). It has been hypothesized that protein glutathionylation may represent a mechanism of redox regulation, in a fashion similar to that mediated by protein phosphorylation. We investigated whether GSH has a signaling role in the respon...