Metabolic pathway and biological significance of glutathione detoxification of aristolochic acid ⅠAAICCK-8 assayNude miceLaser confocalSERSAristolochic acid I (AAI) is a nephrotoxic chemical found in the plant genera,AristolochiaandAsarum. AAI can be reduced to positively charged aristolochyl actam-...
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells☆ Author links open overlay panelHirotaka Imai *, Yasuhito Nakagawa *Show more Share Cite https://doi.org/10.1016/S0891-5849(02)01197-8Get rights and content Abstract Reactive oxygen species ...
Pearson’s correlation analysis was applied to reveal the correlation between the acute toxicity of luminescent bacteria 502 and each conventional parameter [6]. Two significance levels of p < 0.05 and p < 0.01 were used to define statistical significance....
D. Biochemical significance of the hard and soft acids and bases principle. Chem.-Biol. Interact. 23, 65–84 (1978). Article Google Scholar Schwöbel, J. A. H. et al. Measurement and estimation of electrophilic reactivity for predictive toxicology. Chem. Rev. 111, 2562–2596 (2011)....
doi:10.1007/BF01610274Frederick S. HammettSpringer Berlin HeidelbergProtoplasmaHammett , F. S., 1932. The Effect of Radium on Glutathione and its Biological Significance. Protoplasma. In Press.
The glutathione S-transferase Mu (GSTM) gene belongs to the GST gene family, which functions in cell metabolism and detoxification. The relationship between GSTM and COAD and the underlying mechanism remain unknown. Methods: Data extracted from The Cancer Genome Atlas included mRNA expression and ...
The protease-inhibitor complexes seem separated readily by treatment with reduced glutathione or cysteine, and the protease becomes active.Hideo, HayashiThe First Department of Pathology Kumamoto University
Imai HSchool of Pharmaceutical Sciences Kitasato University Tokyo 108-8641 Japan.藥學雜誌Imai H. Biological significance of lipid hydroperoxide and its reducing 30. enzyme, phospholipid hydroperoxide glutathione peroxidase, in mammalian cells. Yakugaku Zasshi. 2004;124(12):937-57....
P. Guengerich, Compari- son of and relationships between glutathione S-transferase and cytochrome p-450 systems, in "Glutathione Conjugation, Mechanisms and Bi- ological Significance" (H. Sies and B. Ketterer, Eds.), p. 193, Academic Press, New York, 1988.Ketterer, B., Meyer, D. J. ...
(eds), Glutathione Conjugation: Mechanisms and Biological Significance. Academic Press, London, pp. 316-356.Morgenstern,R. and De Pierre,J.W. (1988) In Sies,H. and Ketterer,B. (eds), Glutathione Conjugation: Mechanisms and Biological Significance. Academic Press, London, pp. 157-174....