Metabolites detected up to 72 hours after 2 mg tablet Main metabolite: 7-amino-Flunitrazepam Needs to be sent to special lab Hoffmann-La Roche offers free testing General Info: 800-720-1076 Testing: 800-608-6540 VII. Drug Interactions (may be lethal in combination) ...
为较强的镇静催眠药,其作用与硝西泮相似但较之强。亦有较强的肌肉松弛作用。用于手术前镇静及各种失眠症。催眠作用开始快,可持续5—7小时。亦可用作静脉麻醉药(单用或诱导麻醉),诱导时间较长,约135秒,但效果满意。与肌松药箭毒合用,可达稳定麻醉1—2小时。[用法与用量]催眠:口服,2mg,每...
Flunitrazepam在0.5-4mg劑量範圍中,其藥動學 呈線性,每天口服給與造成flunitrazepam在血漿中緩慢蓄積(蓄積比例為 1.6-1.7),5天後可達flunitrazepam的穩定血漿濃度,在給予多次口服劑量2mg 後,flunitrazepam在穩定狀態時的最低血漿濃度為3-4ng/ml,flunitrazepam和 其藥理活性N-desmethyl代謝物在體內達穩定狀態時,其血漿濃度...
The control group received 0.5 ml of distilled water, while the lowand highヾose Rohypnol‐treated groups received 2 mg/kg b.w and 4 mg/kg b.w of Rohypnol via oral lavage once daily for 28 days. Rohypnol significantly increased mount latency, intromission latency, ejaculation latency and ...
In this study, adult male rats were randomized into six groups of six rats each: the control received 1ml of distilled water as vehicle, while the low- and high-dose Rohypnol-treated groups received 2mg/kg and 4mg/kg of Rohypnol for four weeks. The control-, low-, a...