Typical Dosages: 1-2 mg Onset effect 20-30 minutes Peak effect 1-2 hours Sedative Effect after 2 mg tab: 6-8 hours Duration longer when combined with Alcohol or drugs Dissolves in frothy drinks (Daiquiri, Margarita) V. Effects Lower dose (1-2 mg) Relaxes skeletal Muscle and impairs ...
Flunitrazepam在0.5-4mg劑量範圍中,其藥動學 呈線性,每天口服給與造成flunitrazepam在血漿中緩慢蓄積(蓄積比例為 1.6-1.7),5天後可達flunitrazepam的穩定血漿濃度,在給予多次口服劑量2mg 後,flunitrazepam在穩定狀態時的最低血漿濃度為3-4ng/ml,flunitrazepam和 其藥理活性N-desmethyl代謝物在體內達穩定狀態時,其血漿濃度...
为较强的镇静催眠药，其作用与硝西泮相似但较之强。亦有较强的肌肉松弛作用。用于手术前镇静及各种失眠症。催眠作用开始快，可持续5—7小时。亦可用作静脉麻醉药(单用或诱导麻醉)，诱导时间较长，约135秒，但效果满意。与肌松药箭毒合用，可达稳定麻醉1—2小时。[用法与用量]催眠：口服，2mg，每...
In a double-blind, cross-over trial, triazolam (0.25 mg) was tested against flunitrazepam (1 mg) in the typical midwinter insomnia which is often seen among otherwise healthy people in Northern Norway. Each drug was given for five nights, in random order, with a five-night placebo period ...
In a double-blind, cross-over trial, triazolam (0.25 mg) was tested against flunitrazepam (1 mg) in the typical midwinter insomnia which is often seen amon... O Lingjaerde,T Bratlid - 《Acta Psychiatrica Scandinavica》 被引量: 5发表: 2010年 More on Rohypnol. Comment on Can Nurse. 2002...
In this study, adult male rats were randomized into six groups of six rats each: the control received 1ml of distilled water as vehicle, while the low- and high-dose Rohypnol-treated groups received 2mg/kg and 4mg/kg of Rohypnol for four weeks. The control-, low-, a...
In 12 healthy volunteers, the pharmacological effects of midazolam were investigated following intravenous (0.15 mg X kg-1 and 12.5 mg in 6 subjects each), intramuscular (12.5 mg in 6 subjects) and oral administration (20 mg in 6 subjects and 10 mg in 4 subjects). The findings were ...