系统标签: genome rna human guided 基因组 crispr RNA-GuidedHumanGenomeEngineeringviaCas9PrashantMali1,5,LuhanYang1,3,5,KevinM.Esvelt2,JohnAach1,MarcGuell1,JamesE.DiCarlo4,JulieE.Norville1,andGeorgeM.Church1,2,*1DepartmentofGenetics,HarvardMedicalSchool,Boston,MA02115,USA2WyssInstituteforBiologically...
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RNA-Guided Human Genome Engineering via Cas9 DOI: 10.1126/science.1232033 , 823 (2013);339 Science et al.Prashant Mali RNA-Guided Human Genome Engineering via Cas9 This copy is for your personal, non-commercial use only. clicking here.colleagues, clients, or customers by , you can order ...
RNA-Guided Human Genome James E. DiCarlo,4 Engineering via Cas9Mali, PYang, LEsvelt, KAach, JGuell, MDi Carlo, MNorville, JEChurch, George M
simultaneous introduction of multiple gRNAs, can effect multiplex editing of target loci. We also compute a genome-wide resource of ~190 K unique gRNAs targeting ~40.5% of human exons. Our results establish an RNA-guided editing tool for facile, robust, and multiplexable human genome engineering...
Learn about CRISPR Cas9, what it is and how it works. CRISPR is a new, affordable genome editing tool enabling access to genome editing for all.
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RNA-guided human genome engineering via Cas9. Science published online (3 January 2013). Download references Rights and permissions Reprints and permissions About this article Cite this article de Souza, N. RNA-guided gene editing. Nat Methods 10, 189 (2013). https://doi.org/10.1038/nmeth....
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