The positive-sense RNA molecule then acts as viral mRNA, and this mRNA is translated into proteins by host ribosomes. In addition, retroviruses have a ssRNA genome but are generally not considered RNA viruses because they utilize DNA intermediates for replication [23]. The nucleic acid of a ...
into multiprotein complexes and is the predominant isoform in the lung, breast, and kidney, whereas the active ATPase SNF2L, bearing the nucleosome-sliding function, is expressed in brain and skeletal muscle19. To identify which isoform(s) of SNF2L is/are expressed in hepatocytes, we performed...
RNA expression, and protein expression. The approach utilized three steps to identify genes with protein abundance that correlates with RNA abundance and chromatin accessibility. The first step randomizes the samples to two sets. The second step is to visualize ...
(+) strand RNA viruses. These viruses are unique in that theirgenomic RNAis translated immediately upon infection; that is, the virus particle is simply a package that introduces an mRNA molecule into the cell. It is the translation of this RNA, and the resulting synthesis of the virus-...
Of the entire human genome, 90% of all genetic information is transcribed but only afraction of that subsequent RNA is translated into proteins. RNAs which are not translated intoproteins are deemed non-coding RNAs. Little is known about this large category of noncodingRNAs, although they perfor...
【1】DNA or deoxyribonucleic acid is the molecule that codes genetic information. However, DNA can't directly order a cell to make proteins. It has to be transcribed into RNA orribonucleic acid. RNA, in turn, is translated bycell...
RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated [J]. Cancer Lett. 2016;376(1):34–42. Article CAS PubMed Google Scholar Wang XL, Li ZH, Kong BH, et al. Reduced m6A mRNA methylation is correlated with the ...
Translation is reading ___ (DNA/RNA) and using that information to make a protein. Gene Expression: Gene expression is the process by which genetic information from the DNA is translated into protein molecules. These proteins can then provide several different functions within a ce...
form a double-stranded hairpin structure that is commonly targeted for RNA editing [34,56,57]. Although Alu elements are predominantly found in introns and untranslated regions of genes, they are occasionally found in translated regions as well. ADARs are capable of recognizing and binding this RN...
et al. RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated. Cancer Lett. 376, 34–42 (2016). Article CAS PubMed Google Scholar Paris, J. et al. Targeting the RNA m6A reader YTHDF2 selectively compromises cancer stem ...