相关研究结果于2022年6月2日在线发表在Cell期刊上,论文标题为“Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization”。论文通讯作者为哥德堡大学教授Maria Falkenberg和卡罗林斯卡医学院的B. Martin Hällberg。论文第一作者为哥德堡大学的Xuefeng Zhu和Xie Xie以及卡罗林斯卡学院的Hrishi...
than serum HBV RNA in the same individual?[J]. Hepatology, 2021, 73(5): 2075-2076. DOI: 10.1002/hep.31514. [9] Hirsch RC, Lavine JE, Chang LJ, et al. Polymerase gene products of hepatitis B viruses are req...
Upstream signaling initiates transcription of microRNA genes and may createfeedback loopsby targeting their own transcription factor(s). 上游信号启动 microRNA 基因的转录,并可能通过靶向它们自己的转录因子来创建反馈回路。 MiR-200c is involved in ...
et al. IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner. Nucleic Acids Res. 47, 375–390 (2019). Article PubMed CAS Google Scholar Bohnsack, K., Höbartner, C. & Bohnsack, M. Eukaryotic 5-methylcytosine (m5C) RNA methyltransferases: mechanisms...
allowing for investigation of lncRNAs in a way that separates their functions from the effects of their transcription [57]. Another recent adaptation of Cas9 comes from Cheng et al., who have developed a method to tag and manipulate lncRNA expression in vitro. The approach, called CRISPR-CTRL...
In both metazoans and plants, transposons are revealed for transcription and produce small RNAs that target transposons in the germ cells to maintain silencing through nuclear RNAi. In mammals, piRNAs can directde novocytosine methylation in the germ line and have been shown to do so at an impri...
RNA synthesis or transcription is the primary step of gene expression, in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase (RNAP). From:Biomedicine & Pharmacotherapy,2018 About this page Set alert Also in subject areas: ...
Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing Monoclonal antibody 104 recognizes a subset of amphibian nuclear granules (B-snurposomes) and active sites of RNA polymerase II transcription in vertebrate... A Mayeda,AM Zahler,AR Krainer,... - 《...
The process is called transcription and the RNA copy of the gene is called messenger RNA (mRNA). The mRNA is an exact copy of the gene, in which all thymines (T) are replaced with uracils (U). In the second step, called translation, mRNA is used as a template for protein synthesis...
It plays a multifaceted role in shaping gene transcription, protein diversity, and functional adaptability in response to environmental cues. Recent studies demonstrate that drugs of abuse have a profound impact on alternative splicing patterns within different brain regions. Drugs like alcohol and ...