RNA核酸外切酶 Terminator 5'-Phosphate-Dependent Exonuclease Terminator Exonuclease是一种5’→ 3’进行性核酸外切酶,可降解带有5’单磷酸的RNA。它不会降解具有5’三磷酸、5’-帽结构(例如大多数真核mRNA带有的5’-帽结构)或5’OH的RNA。它也消化带有...
前体mRNA 在修十点被切断,假如 polyA tail 和 5’ cap,下游虽然转录但是很快被降解 RNA pol 没有3’-5’ exonuclease 功能,转录有一定错误率 第四节 真核生物前体 RNA 的加工和降解 一、前体 mRNA 经过首、尾修饰、剪接和编辑加工后才能成熟 5‘ cap: 加帽时间:25~30nt 时期 结构:7-甲基鸟嘌呤-ppp-5...
英文名称:Recombinant RNA Exonuclease 2 Homolog (REXO2) 保质期:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。 保存条件:2-8°C不超过一个月,-80°C不超过12个月 RNA核酸外切酶2同源物(REXO2)重组蛋白多年致力于重组蛋白表达,抗体制备研究,我们目前拥有大量的商业化表达载体质粒包括多种标签质粒...
This study hence establishes the molecular basis of ExoG functioning as a unique 5-exonuclease to mediate the flap-independent RNA primer removal process during mtDNA replication to maintain mitochondrial genome integrity.doi:10.1093/nar/gkz241Wu, Chyuan-Chuan...
研究团队首先将该方法应用于wild-type（WT）和m6A甲基转移酶 METTL3敲除（METTL3-KO）HEK293T细胞转录组m6A的鉴定。结果表明，nanopore direct RNA-seq/xPore鉴定的m6A位点与基于二代测序的m6ACE-seq （m6A-cross- linking-exonuclease sequencing ）结果高度一致，90% xPore鉴定出的显著性m6A位点（top significant ...
TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends. PLoS Genet. 8, e1002747 (2012). CAS PubMed PubMed Central Google Scholar Herold, S. et al. Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase. Nature 567, 545–549 (...
2.Akiyama, B.M. et al. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease.Science354, 1148-1152 (2016). 3.MacFadden, A. et al. Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs.Nat. Commun...
RNA纯化柱 商品属性: 产品名称 规格 货号 RNA 纯化柱 100 套 / 包 BJ-PJ6826 Taq DNA Polymerase(7U/ul,Buffer-) 聚合酶 Taq酶 500U×10 Recombinant Human Annexin-8 Greater than 95% by SDS-PAGE gel analyses r
Cryo-electron microscopy structures of intermediates formed during the degradation of the 30S ribosomal unit shed light on how the 3′ to 5′ exonuclease ribonuclease R controls the ribosomal degradation process. Lyudmila Dimitrova-Paternoga ,Sergo Kasvandik ...