A separate editing exonuclease for DNA replication: The ?? subunit of Escherichia coli DNA polymerase III holoenzymedoi:10.1073/pnas.81.24.7747Richard ScheuermannH Echols
英文: During DNA replication, FEN ′→′ exonuclease removes the last nucleoside of RNA primer attached to an Okazaki fragment.中文: 在DNA复制过程中 ,FEN 通过其外切酶、内切酶活力去除了冈崎片段前端RNA引物的最后一个核糖核苷 .英文: SPR Biosensor Study of The Molecular Recognition Between The DNA ...
Baculovirusencodes a related alkaline exonuclease, and null mutants in this gene display similar defects in DNA processing, resulting in aberrantencapsidationand nuclear egress (Okano et al., 2007). Thus, the role of viral alkaline exonucleases inDNA replicationmay be evolutionarily conserved among dif...
Measurement of the HAP-induced reversion frequency of the ura3 alleles placed into chromosome III near to the defined active replication origin ARS306 in two orientations indicated that DNA polymerases epsilon and delta correct HAP-induced DNA replication errors on opposite DNA strands. 展开 关键词:...
EXONUCLEASE TREX1DNA-REPLICATIONMUTATIONSVPXSAM domain and HD domain-containing protein 1 (SAMHD1) is a dGTP-dependent triphosphohydrolase that degrades ... V Tüngler,W Staroske,B Kind… - 《Journal of Molecular Medicine Jmm》 被引量: 110发表: 2013年 Activation of cyclic GMP-AMP synthase ...
−>5′ exonuclease domains, and detect a mismatch in a newly synthesized strand to remove it in cooperation with Proliferating cell nuclear antigen (PCNA), which encircles the DNA to provide a molecular platform for efficient protein–protein and protein–DNA interactions during DNA replication and...
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a slidi...
The DNA mismatch repair (MMR) pathway identifies and corrects small insertions, deletions, and misincorporations that arise within the genome as a result of errors during DNA replication. The process by which MMR corrects these mispairs includes recognition of the mispair by the MutS complex, ...
DNA polymerase (DNAP) can correct errors in DNA during replication by proofreading, a process critical for cell viability. However, the mechanism by which ... G Buchel,AR Nayak,K Herbine,... - 《Nature Communications》 被引量: 0发表: 2023年 Networked Communication between Polymerase and Exo...
Detection of specific polymerase chain reaction product by utilizing the 5'---3' exonuclease activity of Thermus aquaticus DNA poly... Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient muta......