The codon chart outlines the various codon combinations and their corresponding amino acids. To use the codon chart, for example, if the first codon position contains uracil (U), the second contains adenine (A), and the third contains cytosine (C), the resulting codon, UAC, represents the a...
through comparisons of protein amino acid sequences, functional domains and structures predicted by AlphaFold44, we found that RH11, RH37, and RH52 are orthologous to the yeast Ded1p and human DDX3X (Extended Data Fig.8b–d). The sequence and structural homology to the yeast Ded1p also ali...
each cleaned read is translated into dozens of peptide sequences using all possible reading frames. In addition to finding the true peptide among these, Seq2Fun must also consider many other sequences that capture amino acid substitutions and deletions because the reference...
RNA-seq-based diagnostic flow chart. Flow diagram showing the diagnostic decision guideline after detecting a gene with an aberrant event in RNA-seq data. Identification of an aberrant event can lead to genetic diagnosis (diagnostic setting), lead to the discovery of a candidate new disease gene...
A pie chart showing distribution of top BLAST hits of Cimex lectularius sequences. (TIFF 68 KB) 12864_2011_3839_MOESM3_ESM.TIFF Additional file 3: Distribution of Cimex lectularius GO categories. Distribution of GO categories for biological process, cellular component and molecular function. BB...
g Pie chart indicates the fraction of reads in ILF3 HepG2 eCLIP mapping (green) with fewer mismatches to rmiR-663, or (gray) mapping equally well to rmiR-663 and other miR-663 family members as indicated. See Additional file 3: Fig. S3j-k for LIN28B (HepG2) and SSB (HepG2)....
FIG. 2 (A-C) show lysis fluorescence micrographs and (D) shows a lysis efficiency chart; FIG. 3 (A-D) shows total ion chromatogram (TIC) obtained by gas chromatography coupled to mass spectrometry; FIG. 4 (A-B) shows electropherograms and associated gels of RNA fractions isolated using...
As discussed above, the non-coding transcripts that do not encode proteins and are more than 200 nucleotides in length are known as long non-coding RNAs (lncRNAs). The length of a lncRNA can be more than 2 Kb while their coding potential is less than 100 amino acids [5]. Kaur and co...
DNA,RNA,Protein遗传物质 DNA,RNAandProtein HowtheInformationinDNAIsUsedtoBuildaProtein InformationFlowFromDNA Replication (priortonucleardivision)Gene:sequenceofDNAthatcodesforaprotein DNAtranscriptionRNAtranslation Protein (maintaincellmetabolismandsupportgrowth)DNAandRNAStructure DNA PrimaryStructureSecondaryStructure...
B Bar chart showing the enrichment of specific pathways, based on the HALLMARK, GO-BP and KEGG gene sets of upregulated and downregulated genes in high-immune reactive status samples compared with low status samples. C Violin plots showing immune surveillance score and expressions of MHC class I...