Frederick C. NeidhardtElsevier Inc.Biochem Biophys Res CommunNEIDHARDT, F. C. 1962. Role of amino acids in regulating RNA formation. Biochem. Biophys. Res. Commun. 7:361-365.NEIDHARDT FC. Role of amino acids in regulating RNA formation. Biochem Biophys Res Commun. 1962 May 11; 7 :361–...
Finally, we suggest the identification of an additional amino acid involved in base-pair recognition by the demonstration that the replacement of Arg-96 with alanine specifically suppresses an A.T---G.C promoter down mutation at position -12. The identification of amino acids that are four resid...
Humans derive a small fraction of their oxidative energy from the catabolism of amino acids. Amino acids are derived from the normal breakdown (recycling) of cellular proteins, degradation of ingested proteins, and breakdown of body proteins in lieu of other fuel sources during starvation or in un...
1. Four major nucleotide (CMP, AMP, GMP and UMP) materials obtained from alkali digests of a purified specimen of acid precipitable yeast RNA by ion exchange chromatography were found to contain a small but significant amount of peptides in bound form. The bound peptides are not confined to...
Amino acids are a crucial, yet basic unit of protein, and they contain an amino group and a carboxylic group. They play an extensive role in gene expression process, which includes an adjustment of protein functions that facilitate messenger RNA (mRNA) translation. ...
Precursors to the tRNA are transcribed from DNA by RNA polymerase III. Another key in the formation of proteins is the attachment of amino acids to the specific tRNA. Specific enzymes called aminoacyl-tRNA synthetases couple the amino acid to the appropriate tRNA. There is a different synthetase...
Any of a large number of compounds that are found in living cells, contain carbon, oxygen, hydrogen, and nitrogen, and join together to form proteins. ♦ About 20 amino acids are needed by animal cells to produce proteins, but only about half, callednonessential amino acids, can be produ...
groups, -COOH. The alpha-amino acids RCH(NH2)COOH (where R is either hydrogen or an organic group) are the component molecules of proteins; some can be synthesized in the body (nonessential amino acids) and others cannot and are thus essential components of the diet (essential amino acids...
Small RNA helices as substrates for aminoacylation and their relationship to charging of transfer RNAs Aminoacyl-tRNA synthetases are structurally diverse enzymes that catalyze the specific attachment of amino acids to the 3鈥 ends of transfer RNAs [1, 2]. B... C Francklyn,K Musier-Forsyth,P ...
While glucose is a renowned energy source for cancer growth, amino acids are also important fuels supporting cancer development. Glutamine, for example, is largely anaplerotic and relinquishes both amine groups to support the TCA cycle2. In addition to glutamine, other amino acids can function as...