TGFβ-treated NMuMG-ErbB2 cells harbouring a LucA-shRNA readily degraded the gelatin substrate, while loss of LPP (LPP-shRNA) abrogated the degradative ability of these cells (Fig. 3b and see Supplementary Fig. 5b). LPP is composed of three carboxy-terminal LIM (LIN-11, ISL-1, MEC-3...
The human genome contains more than 30,000 lncRNA genes, which are expressed into more than 100 thousand transcripts (https://www.gencodegenes.org/human/stats_45.html5,48). Although the mechanism of transcription initiation and termination can be different from those of mRNAs,49most lncRNAs ar...
5.the cytoskeleton is composed of very fine ___, medium ___and larger ___. 6.Creeping and gliding cell movements are usually ___-dependent. 7.___ behavior is shown when a cell moves toward or away from a chemical substances. 8.Flagella grow from the cell surface only at the __...
et al. Lyophilization is suitable for storage and shipment of fresh tissue samples without altering RNA and protein levels stored at room temperature. Amino Acids 43, 1383–1388 (2012). https://doi.org/10.1007/s00726-011-1212-8 Download citation Received02 August 2011 Accepted27 December 2011...
greatly affecting the extracellular matrix composition. Also, RNA-sequencing analysis showed that PNPase is involved in the regulation of distinct pathways influencing biofilm formation, namely quorum sensing and metabolism of carbohydrates and amino acids. Hence, we present PNPase as a new biofilm regu...
Most of the PMU-like regions detected in the SA-1 strain genome were located at the beginning or at the end of the contig, while some of the assembled contigs were entirely composed of a PMU-like region (Fig. 1). The largest PMU cluster was 18 kbp (Fig. S6A) corresponding to an ...
Spore wraps are multilayered, and usually are distinguished from spore core to external medium. They are composed of an internal membrane, a cortex, an external membrane, a coat, and possibly an exosporium. Each layer presents specific structural, biochemical, and permeability properties (Remize,...
This premature stop codon results in a truncated Scl1.3 variant composed of 102 amino acids (~11.4 kDa), which does not contain the cell wall-membrane (WM) associated region, thus, preventing it from anchoring to the bacterial cell surface (Figure 1b). This prompted us to investigate the ...
Determination of the crystal structure of human eRF1 has shown that it is composed of three domains and resembles by overall shape and dimensions a tRNA molecule with the N-terminal and middle domains corresponding to the tRNA's anticodon stem and aminoacyl acceptor stem, respectively [7]. eRF...
The Trail Making Test (TMT) is composed by the subtests TMTA and TMTB. The TMTA (TMTA, greater focus on attention) consisted of a standardized page in which numbers 1 to 25 are scattered within the circles, and participants were asked to connect the numbers in order as quickly as possible...