Hausmann S, Shuman S. Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2) Journal of Biological Chemistry . 2005; 280 (37):32101–32106.Hausmann S, Shuman S (2005) Giardia Lamblia RNA Cap Guanine-N2 Methyltransferase (Tgs2) . J Biol Chem 280 : 32101–32106...
The deduced amino acid sequence of the 888-nucleotide N69 cDNA fragment originally isolated fromPaspalum notatum[23] showed strong homology with the RNA-cap guanine-N2 methyltransferase domain (PF09445;E-value: 1.4 × 10−46) [23]. In yeast, mammalian, andDrosophilagenomes, PF09445 is enco...
Hausmann S, Shuman S: Specificity and Mechanism of RNA Cap Guanine-N2 Methyltransferase (Tgs1). J Biol Chem 2005,280(6):4021-4024. 10.1074/jbc.C400554200. Article CAS PubMed Google Scholar Lobo SM, Lister J, Sullivan ML, Hernandez N: The cloned RNA polymerase II transcription factor II...
cap3. RNA capping in CoVs involves activities of several nonstructural proteins (nsps): nsp13, a bifunctional RNA/NTP triphosphatase (TPase) and helicase; nsp14, a bifunctional 3′→5′ mismatch exonuclease, and mRNA cap guanine-N7 methyltransferase; nsp16, a cap ribose 2′-O ...
(for example, in the nucleus versus the cytoplasm), processed, and folded to function correctly [124,125]. Localization should be verified using techniques like RNA FISH, while polyadenylation and 5′ capping can be examined by RNA-seq [126] and monitoring guanine-N7 methyltransferase activity ...
MGMT O-6-methylguanine-DNA methyltransferase MKI67 marker of proliferation Ki-67 MLANA melan-A MLF1 myeloid leukemia factor 1 MLH1 mutL homolog 1 MLLT3 MLLT3, super elongation complex subunit MME membrane metalloendopeptidase MMP1 matrix metallopeptidase 1 MMP3 matrix metallopeptidase 3 MMP7 matrix ...
Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in...
Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in...
andguaninemethyltransferase(housed on the D2 subunit). The coordinated action of the all three activities results in the synthesis of CAP 0. mRNA CAP2′-O-Methyltransferase transfers a methyl group fromSAMto the 2′ position of the first nucleotide connected to the CAP, creating CAP 1 and com...
HAUSMANN Stephane u.a.: Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe. In: Nucleic Acids Research, 35, 2007, 5, 1411–1420. Attorney, Agent or Firm: POHL & PARTNER Patentanwälte (Hamburg, DE) Claims...