tRNA-guanine transglycosylase (TGT) is a key enzyme involved in the posttranscriptional modification of tRNA across the three kingdoms of life. In eukaryotes and eubacteria, TGT is involved in the introduction of queuine into the anticodon of the cognate tRNAs. In archaebacteria, TGT is responsib...
www.nature.com/cddis ARTICLE OPEN A novel 3'tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer Huaiping Cui1,2,3, Han Li4, Hao Wu1, Fengying Du 1, Xiaozhou Xie2, Shujie Zeng1, Zihao Zhang1, Kangdi Dong2, Liang Shang1,2...
Transfer RNAs (tRNAs) are transcribed as precursor molecules that undergo several maturation steps before becoming functional for protein synthesis. One such processing mechanism is the enzyme-catalysed splicing of intron-containing pre-tRNAs. Eukaryotic
Karin Musier-ForsythElsevier B.V.《Biochimica Et Biophysica Acta Proteins & Proteomics》Burke,B., An,S. and Musier-Forsyth,K. (2008) Functional guanine-arginine interaction between tRNAPro and prolyl-tRNA synthetase that couples binding and catalysis. Biochim. Biophys. Acta, 1784, 1222-1225....
2003. tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5Ј end of tRNAHis. Genes Dev. 17:2889-2901.W. Gu, J. E. Jackman, A. J. Lohan, M. W. Gray, E. M. Phizicky, tRNAHis maturation: An essen- tial yeast protein catalyzes addition...
TierneyDavid L.BiochemistryGarcia GA, Tierney DL, Chong SR, Clark K, PennerHahn JE. X-ray absorption spectroscopy of the zinc site in tRNA-guanine transglycosylase from Escherichia coli. Biochemistry. 1996; 35:3133-3139. [PubMed: 8608154]...