Polynucleotides encoding RING/U-Box superfamily proteins, polypeptides encompassing RING/U-Box superfamily proteins, and expression constructs for expressing genes of interest whose expression may improve agronomic properties including but not limited to crop yield, biotic and abiotic stress tolerance, and ...
The TRIM superfamily exhibits a highly conserved order of domains in the RBCC motif, comprising a RING domain, one or two B-box (BB) domains, and a coiled-coil (CC) domain.31The BB domains of TRIMs are also zinc-binding motifs, whereas the function of BB domains remains less so far k...
the VHL protein is replaced by one of many known BC-box proteins, including members of the family of more than 30suppressors of cytokine signaling proteins, which play important roles in a variety ofsignal transductionpathways. Sign in to download full-size image...
L Wei,MH Bengtson,U Axel,... - 《Plos One》 被引量: 865发表: 2008年 TRIM/RBCC, a novel class of ‘single protein RING finger’ E3 ubiquitin ligases The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a RING domain, one or two B-box motifs and ...
RING finger domains from a number of proteins have been shown to function as E3 ubiquitin ligases wherein they mediate protein-protein interactions with E2 ubiquitin ligases [11]. Besides the well acknowledged role of RING fingers in the ubiquitination pathway, the B-box and the Zf-UBP are ...
According to domain organization and the ability to carry thioester-linked Ub, E3 ligases can be divided into 4 types: HECT, RING, U-box, and RBR4. RING-type E3 ligases are characterized by the presence of a RING domain, which was first identified in a protein encoded by the Really ...
At2g19410 U-box domain-containing protein kinase family protein Protein ubiquitination −0.58 n.c. L At1g32850 UBP11, UBIQUITIN-SPECIFIC PROTEASE11 Ubiquitin-dependent protein catabolic process −0.55 n.c. L At4g22285 Ubiquitin C-terminal hydrolases superfamily protein Ubiquitin-dependent protein ...
Polynucleotides encoding RING/U-Box superfamily proteins, polypeptides encompassing RING/U-Box superfamily proteins, and expression constructs for expressing genes of interest whose expression may improve agronomic properties including but not limited to crop yield, biotic and abiotic stress tolerance, and ...
As inflammation precedes fibrosis in fibroproliferative conditions, it was important to understand how ILB®might modulate inflammatory and tissue remodelling pathways in human cells. Protein and gene expression data from relevant cultured human cells suggest that, through reprogramming immune activation, ...
E3 enzymes, which play essential roles in determining substrate specificity, are classified into the following four main subfamilies based on their subunit composition and mechanism of action: homologous to the E6-associated protein carboxyl terminus (HECT), really interesting new gene (RING), U-box...