against Mycobacterium species, including M. tuberculosis. Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori, M. avium complex, Chlamydia, and other bacteria. It is also useful in co-infections with human immunodeficiency virus, including tuberculosis...
Sustained intragastric antibiotic exposure is important for Helicobacter pylori eradication, yet little is known about gastric pharmacology of commonly used H. pylori regimens. For rifabutin, differing intragastric concentrations based on dosing regimen may account for differences in reported eradication rates...
M1090 Rifabutin Resistance of H. pylori Isolated from Japanese PatientsA 22 year old male presented with symptoms of gastric outlet obstruction. Endoscopy showed a hypertrophic nodular lesion around the pyloric opening with pyloric stenosis. The endoscopic biopsy and histopathological examination revealed ...
Treatment of H. pylori infections in combination with other agents. NON-FDA APPROVED USES NON-FDA APPROVED USES NON-FDA APPROVED USES Treatment of disseminated MAC in patients with AIDS (in combination with a macrolide plus ethambutol). Treatment of TB in patients with AIDS who are taking PIs ...
unchanged drug accounting for about 8 to 9% of the administered dose. Systemic clearance was reported as 0.81 L/h/kg and renal clearance as 0.18 L/h/kg in healthy volunteers. The reported mean plasma elimination half-life varies between individuals and studies, ranging from 32 to 67 hours....
Rifabutin-d7 is intended for use as an internal standard for the quantification of rifabutin by GC- or LC-MS. Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori, M. avium complex, Chlamydia, and other bacteria.1,2,3 ...
Sa1918 Fourth-Line Rescue Therapy With Rifabutin in Patients With Three H. pylori Eradication Failures 喜欢 0 阅读量: 11 作者:JP Gisbert,M Castro-Fernandez,AP Aisa,A Cosme,Javier Molina-Infante,Luis Rodrigo,Ines Modolell,Jose Luis Cabriada,JoseLuis Gisbert,Eloisa Lamas ...
Rifabutin- and furazolidone-based Helicobacter pylori eradication therapies after failure of standard first- and second-line eradication attempts in dyspepsia patients. Aliment Pharmacol Ther 2005;21:91-6... A Qasim,S Sebastian,O Thornton,... - 《Alimentary Pharmacology & Therapeutics》 被引量: 35...
H. pylorimultidrugresistancerifabutinBackground Helicobacter pylori resistance to more than one antibiotic is the main reason for failure in bacterial eradication in a considerable number of patients. Rifabutin (RFB) with a broad‐spectrum of antimicrobial therapy has been suggested for treatment of ...
as a first-line or rescue treatment for H. pylori. The purpose of this study was to evaluate the efficacy and safety of dual therapy vesus rifabutin-containing triple therapy versus classical bismuth-containing quadruple therapy as rescue therapy for the eradication of refractory Helicobacter pylori...