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Animals have endogenous clocks that regulate their behavior and physiology. These clocks rely on environmental cues (time givers) that appear approximately every 24 h due to the Earth’s rotation; thus, most insects exhibit a circadian rhythm. One notable exception is the scarab beetle, Holotrich...
Besides generating vision, light modulates various physiological functions, including mood. While light therapy applied in the daytime is known to have anti-depressive properties, excessive light exposure at night has been reportedly associated with depr
All data were analyzed by Prism 8.0 (GraphPad, USA). In the animal experiment, the comparison between two groups of data was conducted using student t-test (as each group of animals is independent). The three biological replicates in the cell experiment were analyzed using paired t-test (wit...
Circadian clocks in mammals function in most organs and tissues throughout the body. Various renal functions such as the glomerular filtration and excretion of electrolytes exhibit circadian rhythms. Although it has been reported that the expression of t
Key genes controlling circadian clocks include Circadian clocks-associated 1 (CCA1), Late elongated hypocotyl (LHY), and Pseudo response regulators (PRRs) etc [14]. Initially, studies confirmed that CCA1 is a transcription factor binding to the promoter region of Lhcb1.3 gene of A. thaliana. ...
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However,the shoot and root clocks are synchronized under normal day/night conditions,possibly by circulating metabolic signals,making the root clock essentially a "slave" to the shoot clock.doi:10.1126/science.322.5909.1753gNoneScience, AAAS, Washington, DC 20005, U...
Disruption of circadian rhythm during pregnancy produces adverse health outcomes in offspring; however, the role of maternal circadian rhythms in the immune system of infants and their susceptibility to inflammation remains poorly understood. Here we sho